Pechmann Reaction Promoted by Boron Trifluoride Dihydrate
The Pechmann reaction of substituted phenols 1a-e with methyl acetoacetate (2) can be activated by boron trifluoride dihydrate (3) to give the corresponding 4-methyl- coumarin derivatives 4a-e in excellent yield (98-99 %).
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2005-08-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/10/7/762/ |
| Summary: | The Pechmann reaction of substituted phenols 1a-e with methyl acetoacetate (2) can be activated by boron trifluoride dihydrate (3) to give the corresponding 4-methyl- coumarin derivatives 4a-e in excellent yield (98-99 %). |
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| ISSN: | 1420-3049 |