EphA4 blockers promote axonal regeneration and functional recovery following spinal cord injury in mice.
Upregulation and activation of developmental axon guidance molecules, such as semaphorins and members of the Eph receptor tyrosine kinase family and their ligands, the ephrins, play a role in the inhibition of axonal regeneration following injury to the central nervous system. Previously we have dem...
Main Authors: | Yona Goldshmit, Mark D Spanevello, Sophie Tajouri, Li Li, Fiona Rogers, Martin Pearse, Mary Galea, Perry F Bartlett, Andrew W Boyd, Ann M Turnley |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3172248?pdf=render |
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