Fertility in Breast Cancer Survivors in the Middle East: A Retrospective Study
Introduction: By the time they complete breast cancer therapy, many young patients are still of childbearing age. We aim to estimate the incidence of pregnancies in women who completed treatment and examine the percentage of patients who received fertility counseling before initiation of therapy. Ma...
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doaj-120b79d0e8204fe8a830b7b914b801772020-11-25T04:08:32ZengElsevierBreast1532-30802020-08-01525863Fertility in Breast Cancer Survivors in the Middle East: A Retrospective StudyHazem I. Assi0Rasha T. Kakati1Rose Mary Attieh2Jessica Khoury3Fares Sukhon4Juliett Berro5Eman Sbaity6Ziad Salem7Arafat Tfayli8Ibrahim A. Alameh9Nagi El Saghir10Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon; Corresponding author. Associate Professor of Medicine, Department of Internal Medicine, Division of Hematology and Oncology, Naef K. Basile Cancer Center, American University of Beirut Medical Center, P.O. Box: 11-0236, Riad El Solh, 1107 2020, Beirut, Lebanon.Faculty of Medicine, American University of Beirut, Beirut, LebanonDepartment of Internal Medicine, American University of Beirut Medical Center, Beirut, LebanonDepartment of Internal Medicine, American University of Beirut Medical Center, Beirut, LebanonDepartment of Internal Medicine, American University of Beirut Medical Center, Beirut, LebanonDepartment of Internal Medicine, American University of Beirut Medical Center, Beirut, LebanonDepartment of Surgery, American University of Beirut Medical Center, Beirut, LebanonDepartment of Internal Medicine, American University of Beirut Medical Center, Beirut, LebanonDepartment of Internal Medicine, American University of Beirut Medical Center, Beirut, LebanonDepartment of Internal Medicine, American University of Beirut Medical Center, Beirut, LebanonDepartment of Internal Medicine, American University of Beirut Medical Center, Beirut, LebanonIntroduction: By the time they complete breast cancer therapy, many young patients are still of childbearing age. We aim to estimate the incidence of pregnancies in women who completed treatment and examine the percentage of patients who received fertility counseling before initiation of therapy. Material and methods: Electronic health records of breast cancer patients between 2008 and 2014 at AUBMC were screened for exclusion criteria of having metastatic disease or known infertility, still receiving therapy, and being above 42 years at diagnosis. Data about therapy and tumor characteristics was obtained for the included survivors who were interviewed as well via telephone for information about fertility preservation counseling, pregnancy occurrence, and delivery. Results: 451 breast cancer patients were identified. 39 patients remained after application of exclusion criteria. 30.76% (n = 12) wanted more children at the time of diagnosis. 10.25% (n = 4) of all 39 patients treated for breast cancer achieved one or more pregnancy after a median time of 3.83 years after completion of therapy. 25% (n = 3) of women who wanted more children at diagnosis (n = 12) were able to conceive. 23.07% (n = 9) of patients discussed fertility with their primary oncologist prior to treatment initiation. 35.89% (n = 14) of patients were aware of fertility preservation technique availability, but none of these patients used one. Conclusions: The observed rate of pregnancy is comparable to the literature. There is a lack in fertility counseling of breast cancer patients, and the rate of use of fertility preservation techniques is very low despite prior knowledge about their availability.http://www.sciencedirect.com/science/article/pii/S0960977620301065Breast cancerPregnancyFertilityCounselingFertility preservationChemotherapy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Hazem I. Assi Rasha T. Kakati Rose Mary Attieh Jessica Khoury Fares Sukhon Juliett Berro Eman Sbaity Ziad Salem Arafat Tfayli Ibrahim A. Alameh Nagi El Saghir |
spellingShingle |
Hazem I. Assi Rasha T. Kakati Rose Mary Attieh Jessica Khoury Fares Sukhon Juliett Berro Eman Sbaity Ziad Salem Arafat Tfayli Ibrahim A. Alameh Nagi El Saghir Fertility in Breast Cancer Survivors in the Middle East: A Retrospective Study Breast Breast cancer Pregnancy Fertility Counseling Fertility preservation Chemotherapy |
author_facet |
Hazem I. Assi Rasha T. Kakati Rose Mary Attieh Jessica Khoury Fares Sukhon Juliett Berro Eman Sbaity Ziad Salem Arafat Tfayli Ibrahim A. Alameh Nagi El Saghir |
author_sort |
Hazem I. Assi |
title |
Fertility in Breast Cancer Survivors in the Middle East: A Retrospective Study |
title_short |
Fertility in Breast Cancer Survivors in the Middle East: A Retrospective Study |
title_full |
Fertility in Breast Cancer Survivors in the Middle East: A Retrospective Study |
title_fullStr |
Fertility in Breast Cancer Survivors in the Middle East: A Retrospective Study |
title_full_unstemmed |
Fertility in Breast Cancer Survivors in the Middle East: A Retrospective Study |
title_sort |
fertility in breast cancer survivors in the middle east: a retrospective study |
publisher |
Elsevier |
series |
Breast |
issn |
1532-3080 |
publishDate |
2020-08-01 |
description |
Introduction: By the time they complete breast cancer therapy, many young patients are still of childbearing age. We aim to estimate the incidence of pregnancies in women who completed treatment and examine the percentage of patients who received fertility counseling before initiation of therapy. Material and methods: Electronic health records of breast cancer patients between 2008 and 2014 at AUBMC were screened for exclusion criteria of having metastatic disease or known infertility, still receiving therapy, and being above 42 years at diagnosis. Data about therapy and tumor characteristics was obtained for the included survivors who were interviewed as well via telephone for information about fertility preservation counseling, pregnancy occurrence, and delivery. Results: 451 breast cancer patients were identified. 39 patients remained after application of exclusion criteria. 30.76% (n = 12) wanted more children at the time of diagnosis. 10.25% (n = 4) of all 39 patients treated for breast cancer achieved one or more pregnancy after a median time of 3.83 years after completion of therapy. 25% (n = 3) of women who wanted more children at diagnosis (n = 12) were able to conceive. 23.07% (n = 9) of patients discussed fertility with their primary oncologist prior to treatment initiation. 35.89% (n = 14) of patients were aware of fertility preservation technique availability, but none of these patients used one. Conclusions: The observed rate of pregnancy is comparable to the literature. There is a lack in fertility counseling of breast cancer patients, and the rate of use of fertility preservation techniques is very low despite prior knowledge about their availability. |
topic |
Breast cancer Pregnancy Fertility Counseling Fertility preservation Chemotherapy |
url |
http://www.sciencedirect.com/science/article/pii/S0960977620301065 |
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