A case of toxic epidermal necrosis–like cutaneous eruption as the first manifestation and clue to the diagnosis of systemic lupus erythematosus: A case report
We present a rare case of a 61-year-old woman presenting with a widespread erosive eruption on her torso and extremities. Although the lesions were histologically compatible with toxic epidermal necrolysis, clinically the patient was hemodynamically stable, had no mucosal involvement and had no rele...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2020-07-01
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| Series: | SAGE Open Medical Case Reports |
| Online Access: | https://doi.org/10.1177/2050313X20940420 |
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doaj-122c9919f047467ebbb32b889addd5f32020-11-25T03:54:42ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2020-07-01810.1177/2050313X20940420A case of toxic epidermal necrosis–like cutaneous eruption as the first manifestation and clue to the diagnosis of systemic lupus erythematosus: A case reportHanieh Zargham0Stephanie Ghazal1Kevin Watters2Khue Huu Nguyen3Division of Dermatology, Montreal General Hospital, McGill University Health Centre, Montreal, QC, CanadaFaculty of Medicine, McGill University, Montreal, QC, CanadaDepartment of Pathology, McGill University Health Centre, Montreal, QC, CanadaMontreal General Hospital, McGill University Health Centre, Montreal, QC, CanadaWe present a rare case of a 61-year-old woman presenting with a widespread erosive eruption on her torso and extremities. Although the lesions were histologically compatible with toxic epidermal necrolysis, clinically the patient was hemodynamically stable, had no mucosal involvement and had no relevant medical history or potentially incriminating medications. Further investigations uncovered a new diagnosis of systemic lupus erythematosus, with this toxic epidermal necrolysis–like eruption being the first presentation of the disease. This case highlights the importance of broadening the differential diagnosis in patients presenting with acute widespread cleavage of the epidermis, using the spectrum of acute syndrome of apoptotic pan-epidermolysis as a reference.https://doi.org/10.1177/2050313X20940420 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Hanieh Zargham Stephanie Ghazal Kevin Watters Khue Huu Nguyen |
| spellingShingle |
Hanieh Zargham Stephanie Ghazal Kevin Watters Khue Huu Nguyen A case of toxic epidermal necrosis–like cutaneous eruption as the first manifestation and clue to the diagnosis of systemic lupus erythematosus: A case report SAGE Open Medical Case Reports |
| author_facet |
Hanieh Zargham Stephanie Ghazal Kevin Watters Khue Huu Nguyen |
| author_sort |
Hanieh Zargham |
| title |
A case of toxic epidermal necrosis–like cutaneous eruption as the first manifestation and clue to the diagnosis of systemic lupus erythematosus: A case report |
| title_short |
A case of toxic epidermal necrosis–like cutaneous eruption as the first manifestation and clue to the diagnosis of systemic lupus erythematosus: A case report |
| title_full |
A case of toxic epidermal necrosis–like cutaneous eruption as the first manifestation and clue to the diagnosis of systemic lupus erythematosus: A case report |
| title_fullStr |
A case of toxic epidermal necrosis–like cutaneous eruption as the first manifestation and clue to the diagnosis of systemic lupus erythematosus: A case report |
| title_full_unstemmed |
A case of toxic epidermal necrosis–like cutaneous eruption as the first manifestation and clue to the diagnosis of systemic lupus erythematosus: A case report |
| title_sort |
case of toxic epidermal necrosis–like cutaneous eruption as the first manifestation and clue to the diagnosis of systemic lupus erythematosus: a case report |
| publisher |
SAGE Publishing |
| series |
SAGE Open Medical Case Reports |
| issn |
2050-313X |
| publishDate |
2020-07-01 |
| description |
We present a rare case of a 61-year-old woman presenting with a widespread erosive eruption on her torso and extremities. Although the lesions were histologically compatible with toxic epidermal necrolysis, clinically the patient was hemodynamically stable, had no mucosal involvement and had no relevant medical history or potentially incriminating medications. Further investigations uncovered a new diagnosis of systemic lupus erythematosus, with this toxic epidermal necrolysis–like eruption being the first presentation of the disease. This case highlights the importance of broadening the differential diagnosis in patients presenting with acute widespread cleavage of the epidermis, using the spectrum of acute syndrome of apoptotic pan-epidermolysis as a reference. |
| url |
https://doi.org/10.1177/2050313X20940420 |
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