Clinical features and endoscopic findings of pituicytoma in the sellar region: A case report and review of the literature

We report a rare case of pituicytoma occurring in the sellar region resected by endoscopic transsphenoidal surgery (ETSS). We suggest useful indicators for the accurate diagnosis and pitfalls for the surgical procedure. A 38-year-old man was admitted to our hospital with polyuria, erectile dysfuncti...

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Main Authors:	Tomoharu Aki, MD, Akihiro Inoue, MD, PhD, Shohei Kohno, MD, PhD, Naoya Nishida, MD, PhD, Shin Yamashita, MD, PhD, Mana Fukushima, MD, PhD, Shirabe Matsumoto, MD, PhD, Satoshi Suehiro, MD, PhD, Masahiro Nishikawa, MD, Saya Ozaki, MD, Seiji Shigekawa, MD, PhD, Hideaki Watanabe, MD, PhD, Riko Kitazawa, MD, PhD, Takeharu Kunieda, MD, PhD
Format:	Article
Language:	English
Published:	Elsevier 2019-06-01
Series:	Interdisciplinary Neurosurgery
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214751918301841

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spelling	doaj-12332c2bf662497dac9f257d02f6c66b2020-11-25T01:16:30ZengElsevierInterdisciplinary Neurosurgery2214-75192019-06-01165861Clinical features and endoscopic findings of pituicytoma in the sellar region: A case report and review of the literatureTomoharu Aki, MD0Akihiro Inoue, MD, PhD1Shohei Kohno, MD, PhD2Naoya Nishida, MD, PhD3Shin Yamashita, MD, PhD4Mana Fukushima, MD, PhD5Shirabe Matsumoto, MD, PhD6Satoshi Suehiro, MD, PhD7Masahiro Nishikawa, MD8Saya Ozaki, MD9Seiji Shigekawa, MD, PhD10Hideaki Watanabe, MD, PhD11Riko Kitazawa, MD, PhD12Takeharu Kunieda, MD, PhD13Department of Neurosurgery, Ehime University School of Medicine, 454 Shitsukawa, Toon, Ehime 791-0295, JapanDepartment of Neurosurgery, Ehime University School of Medicine, 454 Shitsukawa, Toon, Ehime 791-0295, Japan; Corresponding author at: Department of Neurosurgery, Ehime University School of Medicine, 495 Shitsukawa, Toon, Ehime 791-0295, Japan.Department of Neurosurgery, Ehime University School of Medicine, 454 Shitsukawa, Toon, Ehime 791-0295, JapanDepartments of Otolaryngology, Ehime University School of Medicine, 454 Shitsukawa, Toon, Ehime 791-0295, JapanDepartments of Gastroenterology and Metabology, Ehime University School of Medicine, 454 Shitsukawa, Toon, Ehime 791-0295, JapanDivision of Diagnostic Pathology, Ehime University Hospital, 454 Shitsukawa, Toon, Ehime 791-0295, JapanDepartment of Neurosurgery, Ehime University School of Medicine, 454 Shitsukawa, Toon, Ehime 791-0295, JapanDepartment of Neurosurgery, Ehime University School of Medicine, 454 Shitsukawa, Toon, Ehime 791-0295, JapanDepartment of Neurosurgery, Ehime University School of Medicine, 454 Shitsukawa, Toon, Ehime 791-0295, JapanDepartment of Neurosurgery, Ehime University School of Medicine, 454 Shitsukawa, Toon, Ehime 791-0295, JapanDepartment of Neurosurgery, Ehime University School of Medicine, 454 Shitsukawa, Toon, Ehime 791-0295, JapanDepartment of Neurosurgery, Ehime University School of Medicine, 454 Shitsukawa, Toon, Ehime 791-0295, JapanDivision of Diagnostic Pathology, Ehime University Hospital, 454 Shitsukawa, Toon, Ehime 791-0295, JapanDepartment of Neurosurgery, Ehime University School of Medicine, 454 Shitsukawa, Toon, Ehime 791-0295, JapanWe report a rare case of pituicytoma occurring in the sellar region resected by endoscopic transsphenoidal surgery (ETSS). We suggest useful indicators for the accurate diagnosis and pitfalls for the surgical procedure. A 38-year-old man was admitted to our hospital with polyuria, erectile dysfunction and bitemporal hemianopsia. Neuroimaging revealed pituitary tumor in the sellar region, and the enhanced anterior pituitary gland was displaced anteriorly. Gross total resection was achieved using ETSS. Histological findings revealed bipolar spindle cells staining strongly for thyroid transcription factor 1 (TTF-1). We diagnosed the tumor as pituicytoma originated from posterior pituitary. Pituicytoma is difficult to diagnose on routine neuroimaging and pathological analysis, so accurate diagnosis requires identification of the forward deviation of anterior pituitary gland and analysis of immunohistochemical studies using TTF-1. Keywords: Pituicytoma, Forward deviation of anterior pituitary lobe, Thyroid transcription factor 1http://www.sciencedirect.com/science/article/pii/S2214751918301841
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Tomoharu Aki, MD Akihiro Inoue, MD, PhD Shohei Kohno, MD, PhD Naoya Nishida, MD, PhD Shin Yamashita, MD, PhD Mana Fukushima, MD, PhD Shirabe Matsumoto, MD, PhD Satoshi Suehiro, MD, PhD Masahiro Nishikawa, MD Saya Ozaki, MD Seiji Shigekawa, MD, PhD Hideaki Watanabe, MD, PhD Riko Kitazawa, MD, PhD Takeharu Kunieda, MD, PhD
spellingShingle	Tomoharu Aki, MD Akihiro Inoue, MD, PhD Shohei Kohno, MD, PhD Naoya Nishida, MD, PhD Shin Yamashita, MD, PhD Mana Fukushima, MD, PhD Shirabe Matsumoto, MD, PhD Satoshi Suehiro, MD, PhD Masahiro Nishikawa, MD Saya Ozaki, MD Seiji Shigekawa, MD, PhD Hideaki Watanabe, MD, PhD Riko Kitazawa, MD, PhD Takeharu Kunieda, MD, PhD Clinical features and endoscopic findings of pituicytoma in the sellar region: A case report and review of the literature Interdisciplinary Neurosurgery
author_facet	Tomoharu Aki, MD Akihiro Inoue, MD, PhD Shohei Kohno, MD, PhD Naoya Nishida, MD, PhD Shin Yamashita, MD, PhD Mana Fukushima, MD, PhD Shirabe Matsumoto, MD, PhD Satoshi Suehiro, MD, PhD Masahiro Nishikawa, MD Saya Ozaki, MD Seiji Shigekawa, MD, PhD Hideaki Watanabe, MD, PhD Riko Kitazawa, MD, PhD Takeharu Kunieda, MD, PhD
author_sort	Tomoharu Aki, MD
title	Clinical features and endoscopic findings of pituicytoma in the sellar region: A case report and review of the literature
title_short	Clinical features and endoscopic findings of pituicytoma in the sellar region: A case report and review of the literature
title_full	Clinical features and endoscopic findings of pituicytoma in the sellar region: A case report and review of the literature
title_fullStr	Clinical features and endoscopic findings of pituicytoma in the sellar region: A case report and review of the literature
title_full_unstemmed	Clinical features and endoscopic findings of pituicytoma in the sellar region: A case report and review of the literature
title_sort	clinical features and endoscopic findings of pituicytoma in the sellar region: a case report and review of the literature
publisher	Elsevier
series	Interdisciplinary Neurosurgery
issn	2214-7519
publishDate	2019-06-01
description	We report a rare case of pituicytoma occurring in the sellar region resected by endoscopic transsphenoidal surgery (ETSS). We suggest useful indicators for the accurate diagnosis and pitfalls for the surgical procedure. A 38-year-old man was admitted to our hospital with polyuria, erectile dysfunction and bitemporal hemianopsia. Neuroimaging revealed pituitary tumor in the sellar region, and the enhanced anterior pituitary gland was displaced anteriorly. Gross total resection was achieved using ETSS. Histological findings revealed bipolar spindle cells staining strongly for thyroid transcription factor 1 (TTF-1). We diagnosed the tumor as pituicytoma originated from posterior pituitary. Pituicytoma is difficult to diagnose on routine neuroimaging and pathological analysis, so accurate diagnosis requires identification of the forward deviation of anterior pituitary gland and analysis of immunohistochemical studies using TTF-1. Keywords: Pituicytoma, Forward deviation of anterior pituitary lobe, Thyroid transcription factor 1
url	http://www.sciencedirect.com/science/article/pii/S2214751918301841
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Clinical features and endoscopic findings of pituicytoma in the sellar region: A case report and review of the literature

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