Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury

Exosomes, as a type of extracellular vesicle (EV), are lipid bilayer vesicles 20–100 nm in diameter that can cross the blood-brain barrier. Exosomes are important transport vesicles in the human body that participate in many conduction pathways and play an important physiological role. Because of th...

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Main Authors: Xianhui Kang, Ziyi Zuo, Wandong Hong, Hongli Tang, Wujun Geng
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01149/full
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spelling doaj-12372d32c5f64fb7b8958f5c5f3991af2020-11-24T21:51:09ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2019-10-011310.3389/fnins.2019.01149486641Progress of Research on Exosomes in the Protection Against Ischemic Brain InjuryXianhui Kang0Xianhui Kang1Ziyi Zuo2Wandong Hong3Hongli Tang4Wujun Geng5Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Anesthesiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaThe First Clinical College, Wenzhou Medical University, Wenzhou, ChinaDepartment of Gastroenterology and Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaExosomes, as a type of extracellular vesicle (EV), are lipid bilayer vesicles 20–100 nm in diameter that can cross the blood-brain barrier. Exosomes are important transport vesicles in the human body that participate in many conduction pathways and play an important physiological role. Because of their high biocompatibility and low immunogenicity and toxicity, exosomes have attracted increasing attention as an attractive drug delivery system. This article reviews the relevant studies that have shown that exosomes play an important role in protective mechanisms against ischemic brain injury.https://www.frontiersin.org/article/10.3389/fnins.2019.01149/fullexosomesbrain protectionischemic brain injurystrokedrug delivery
collection DOAJ
language English
format Article
sources DOAJ
author Xianhui Kang
Xianhui Kang
Ziyi Zuo
Wandong Hong
Hongli Tang
Wujun Geng
spellingShingle Xianhui Kang
Xianhui Kang
Ziyi Zuo
Wandong Hong
Hongli Tang
Wujun Geng
Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury
Frontiers in Neuroscience
exosomes
brain protection
ischemic brain injury
stroke
drug delivery
author_facet Xianhui Kang
Xianhui Kang
Ziyi Zuo
Wandong Hong
Hongli Tang
Wujun Geng
author_sort Xianhui Kang
title Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury
title_short Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury
title_full Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury
title_fullStr Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury
title_full_unstemmed Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury
title_sort progress of research on exosomes in the protection against ischemic brain injury
publisher Frontiers Media S.A.
series Frontiers in Neuroscience
issn 1662-453X
publishDate 2019-10-01
description Exosomes, as a type of extracellular vesicle (EV), are lipid bilayer vesicles 20–100 nm in diameter that can cross the blood-brain barrier. Exosomes are important transport vesicles in the human body that participate in many conduction pathways and play an important physiological role. Because of their high biocompatibility and low immunogenicity and toxicity, exosomes have attracted increasing attention as an attractive drug delivery system. This article reviews the relevant studies that have shown that exosomes play an important role in protective mechanisms against ischemic brain injury.
topic exosomes
brain protection
ischemic brain injury
stroke
drug delivery
url https://www.frontiersin.org/article/10.3389/fnins.2019.01149/full
work_keys_str_mv AT xianhuikang progressofresearchonexosomesintheprotectionagainstischemicbraininjury
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AT ziyizuo progressofresearchonexosomesintheprotectionagainstischemicbraininjury
AT wandonghong progressofresearchonexosomesintheprotectionagainstischemicbraininjury
AT honglitang progressofresearchonexosomesintheprotectionagainstischemicbraininjury
AT wujungeng progressofresearchonexosomesintheprotectionagainstischemicbraininjury
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