Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury
Exosomes, as a type of extracellular vesicle (EV), are lipid bilayer vesicles 20–100 nm in diameter that can cross the blood-brain barrier. Exosomes are important transport vesicles in the human body that participate in many conduction pathways and play an important physiological role. Because of th...
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doaj-12372d32c5f64fb7b8958f5c5f3991af2020-11-24T21:51:09ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2019-10-011310.3389/fnins.2019.01149486641Progress of Research on Exosomes in the Protection Against Ischemic Brain InjuryXianhui Kang0Xianhui Kang1Ziyi Zuo2Wandong Hong3Hongli Tang4Wujun Geng5Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Anesthesiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaThe First Clinical College, Wenzhou Medical University, Wenzhou, ChinaDepartment of Gastroenterology and Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaDepartment of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaExosomes, as a type of extracellular vesicle (EV), are lipid bilayer vesicles 20–100 nm in diameter that can cross the blood-brain barrier. Exosomes are important transport vesicles in the human body that participate in many conduction pathways and play an important physiological role. Because of their high biocompatibility and low immunogenicity and toxicity, exosomes have attracted increasing attention as an attractive drug delivery system. This article reviews the relevant studies that have shown that exosomes play an important role in protective mechanisms against ischemic brain injury.https://www.frontiersin.org/article/10.3389/fnins.2019.01149/fullexosomesbrain protectionischemic brain injurystrokedrug delivery |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Xianhui Kang Xianhui Kang Ziyi Zuo Wandong Hong Hongli Tang Wujun Geng |
spellingShingle |
Xianhui Kang Xianhui Kang Ziyi Zuo Wandong Hong Hongli Tang Wujun Geng Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury Frontiers in Neuroscience exosomes brain protection ischemic brain injury stroke drug delivery |
author_facet |
Xianhui Kang Xianhui Kang Ziyi Zuo Wandong Hong Hongli Tang Wujun Geng |
author_sort |
Xianhui Kang |
title |
Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury |
title_short |
Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury |
title_full |
Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury |
title_fullStr |
Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury |
title_full_unstemmed |
Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury |
title_sort |
progress of research on exosomes in the protection against ischemic brain injury |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Neuroscience |
issn |
1662-453X |
publishDate |
2019-10-01 |
description |
Exosomes, as a type of extracellular vesicle (EV), are lipid bilayer vesicles 20–100 nm in diameter that can cross the blood-brain barrier. Exosomes are important transport vesicles in the human body that participate in many conduction pathways and play an important physiological role. Because of their high biocompatibility and low immunogenicity and toxicity, exosomes have attracted increasing attention as an attractive drug delivery system. This article reviews the relevant studies that have shown that exosomes play an important role in protective mechanisms against ischemic brain injury. |
topic |
exosomes brain protection ischemic brain injury stroke drug delivery |
url |
https://www.frontiersin.org/article/10.3389/fnins.2019.01149/full |
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