Pressure sensor emulator to improve longterm stability of heart valve testing systems

Fluid mechanical characterization of artificial heart valve prostheses requires reliable measurement of temperature, flow and pressure at normal heart rate. In vitro fatigue test procedures of artificial heart valve prostheses can take several months with up to 400 million cycles to assess valve per...

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Bibliographic Details
Main Authors: Schmidt Wolfram, Tautorat Carsten, Grabow Niels, Kaule Sebastian, Kaminsky Jörg, Schmitz Klaus-Peter
Format: Article
Language:English
Published: De Gruyter 2019-09-01
Series:Current Directions in Biomedical Engineering
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Online Access:https://doi.org/10.1515/cdbme-2019-0124
Description
Summary:Fluid mechanical characterization of artificial heart valve prostheses requires reliable measurement of temperature, flow and pressure at normal heart rate. In vitro fatigue test procedures of artificial heart valve prostheses can take several months with up to 400 million cycles to assess valve performance and durability under simulated cardiac conditions at increased pulse frequency. In both cases, a minimum of user interventions for recalibration are required. In these tests, pressure data are collected for hydrodynamic heart valve characterization and for closed-loop control of pressure loading. In our study, the improvement of commercial heart valve testing systems (Vivitro Pulse Duplicator, Vivitro Labs Inc. and VDT-3600i, BDC Laboratories) is considered by substituting the built-in disposable pressure sensors (lifetime: one week) by longterm stable sensors. The selected highly accurate sensors (86A, TE Connectivity Corp.) provide amplified, linearized, calibrated and temperature compensated analog output signals. Their stainless steel construction allows for high media compatibility with corrosive liquids. Due to different sensitivity characteristics, these sensors are not fully compatible to the testing devices. To overcome this limitation, application-specific emulator interfaces were developed to connect the new sensors to the data acquisition part of the validated valve testing systems. To stay consistent with manufacturer’s device and software specification, we utilized fast analog signal conditioning, including scaling, offset calibration, out of range alarm and status indication. Compared to the originally equipped pressure sensors, emulator parameters, such as pressure range, precision, resolution and accuracy remained unchanged or even improved. For system verification the response characteristic, long-term stability and dynamic properties were examined in comparative studies
ISSN:2364-5504