FGF21 Mediates Mesenchymal Stem Cell Senescence via Regulation of Mitochondrial Dynamics

Mesenchymal stem cell- (MSC-) based therapy is a novel strategy in regenerative medicine. The functional and regenerative capacities of MSCs decline with senescence. Nonetheless, the potential mechanisms that underlie their senescence are not fully understood. This study was aimed at exploring the p...

Full description

Bibliographic Details
Main Authors: Xin Li, Yimei Hong, Haiwei He, Guojun Jiang, Wei You, Xiaoting Liang, Qingling Fu, Shuo Han, Qizhou Lian, Yuelin Zhang
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/4915149