Coffee Intake and Neurocognitive Performance in HIV/HCV Coinfected Patients (ANRS CO13 HEPAVIH)
Coffee is one of the most consumed beverages worldwide. Previous research has demonstrated its neuroprotective effects in the elderly. People coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) experience an accelerated aging process and cognitive impairment, which signifi...
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doaj-1272b91021824d9792670e391d183d8e2020-11-25T03:55:12ZengMDPI AGNutrients2072-66432020-08-01122532253210.3390/nu12092532Coffee Intake and Neurocognitive Performance in HIV/HCV Coinfected Patients (ANRS CO13 HEPAVIH)Saskia Antwerpes0Camelia Protopopescu1Philippe Morlat2Fabienne Marcellin3Linda Wittkop4Vincent Di Beo5Dominique Salmon-Céron6Philippe Sogni7Laurent Michel8Maria Patrizia Carrieri9the ANRS CO13 HEPAVIH Study GroupAix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Économiques & Sociales de la Santé & Traitement de l’Information Médicale, 13385 Marseille, FranceAix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Économiques & Sociales de la Santé & Traitement de l’Information Médicale, 13385 Marseille, FranceService de Médecine Interne et Maladies Infectieuses, CHU de Bordeaux, Université de Bordeaux, 33000 Bordeaux, FranceAix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Économiques & Sociales de la Santé & Traitement de l’Information Médicale, 13385 Marseille, FranceISPED, Inserm, Bordeaux Population Health Research Center, Team MORPH3EUS, UMR 1219, CIC-EC 1401, University of Bordeaux, F-33000 Bordeaux, FranceAix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Économiques & Sociales de la Santé & Traitement de l’Information Médicale, 13385 Marseille, FranceUniversité Paris Descartes, 75006 Paris, FranceUniversité Paris Descartes, 75006 Paris, FranceUMRS 1018, Paris-Saclay University, 94807 Villejuif, FranceAix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Économiques & Sociales de la Santé & Traitement de l’Information Médicale, 13385 Marseille, FranceCoffee is one of the most consumed beverages worldwide. Previous research has demonstrated its neuroprotective effects in the elderly. People coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) experience an accelerated aging process and cognitive impairment, which significantly impair quality of life and may affect disease-related dimensions such as treatment adherence. This study aimed to analyse the relationship between regular coffee intake and neurocognitive performance (NCP) in HIV-HCV coinfected people. We used data from 139 coinfected patients who participated in both the ANRS CO13 HEPAVIH cohort and the HEPAVIH-Psy cross-sectional survey. Linear regression models adjusting for potential sociodemographic (age, gender, educational level), clinical (liver disease status, ongoing HCV treatment, HIV viral load, major depressive disorder) and socio-behavioural (cannabis use) correlates of NCP were used. Our results showed significant, positive associations between elevated coffee intake (ECI) (three or more cups of coffee per day) and NCP in verbal fluency, psychomotor speed (coding) and executive functioning. ECI might therefore preserve neurocognitive functioning in people living with HIV and HCV.https://www.mdpi.com/2072-6643/12/9/2532coffeehepatitis CHIVneurocognitive disorders |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Saskia Antwerpes Camelia Protopopescu Philippe Morlat Fabienne Marcellin Linda Wittkop Vincent Di Beo Dominique Salmon-Céron Philippe Sogni Laurent Michel Maria Patrizia Carrieri the ANRS CO13 HEPAVIH Study Group |
spellingShingle |
Saskia Antwerpes Camelia Protopopescu Philippe Morlat Fabienne Marcellin Linda Wittkop Vincent Di Beo Dominique Salmon-Céron Philippe Sogni Laurent Michel Maria Patrizia Carrieri the ANRS CO13 HEPAVIH Study Group Coffee Intake and Neurocognitive Performance in HIV/HCV Coinfected Patients (ANRS CO13 HEPAVIH) Nutrients coffee hepatitis C HIV neurocognitive disorders |
author_facet |
Saskia Antwerpes Camelia Protopopescu Philippe Morlat Fabienne Marcellin Linda Wittkop Vincent Di Beo Dominique Salmon-Céron Philippe Sogni Laurent Michel Maria Patrizia Carrieri the ANRS CO13 HEPAVIH Study Group |
author_sort |
Saskia Antwerpes |
title |
Coffee Intake and Neurocognitive Performance in HIV/HCV Coinfected Patients (ANRS CO13 HEPAVIH) |
title_short |
Coffee Intake and Neurocognitive Performance in HIV/HCV Coinfected Patients (ANRS CO13 HEPAVIH) |
title_full |
Coffee Intake and Neurocognitive Performance in HIV/HCV Coinfected Patients (ANRS CO13 HEPAVIH) |
title_fullStr |
Coffee Intake and Neurocognitive Performance in HIV/HCV Coinfected Patients (ANRS CO13 HEPAVIH) |
title_full_unstemmed |
Coffee Intake and Neurocognitive Performance in HIV/HCV Coinfected Patients (ANRS CO13 HEPAVIH) |
title_sort |
coffee intake and neurocognitive performance in hiv/hcv coinfected patients (anrs co13 hepavih) |
publisher |
MDPI AG |
series |
Nutrients |
issn |
2072-6643 |
publishDate |
2020-08-01 |
description |
Coffee is one of the most consumed beverages worldwide. Previous research has demonstrated its neuroprotective effects in the elderly. People coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) experience an accelerated aging process and cognitive impairment, which significantly impair quality of life and may affect disease-related dimensions such as treatment adherence. This study aimed to analyse the relationship between regular coffee intake and neurocognitive performance (NCP) in HIV-HCV coinfected people. We used data from 139 coinfected patients who participated in both the ANRS CO13 HEPAVIH cohort and the HEPAVIH-Psy cross-sectional survey. Linear regression models adjusting for potential sociodemographic (age, gender, educational level), clinical (liver disease status, ongoing HCV treatment, HIV viral load, major depressive disorder) and socio-behavioural (cannabis use) correlates of NCP were used. Our results showed significant, positive associations between elevated coffee intake (ECI) (three or more cups of coffee per day) and NCP in verbal fluency, psychomotor speed (coding) and executive functioning. ECI might therefore preserve neurocognitive functioning in people living with HIV and HCV. |
topic |
coffee hepatitis C HIV neurocognitive disorders |
url |
https://www.mdpi.com/2072-6643/12/9/2532 |
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