| Summary: | AIM: To observe the clinical effect of bio-amnion implantation used in combined trabeculectomy for refractory glaucoma METHODS: Totally 86 eyes of 80 glaucoma patients were randomly divided into 2 groups. In experimental group, 43 eyes underwent trabeculectomy combined with bio-amnion implantation. In control group, 43 eyes only underwent trabeculectomy combined. The intraocular pressure(IOP), filtrative bleb and complications were observed. RESULTS: Following-up for 12 months, IOP: there was significant difference between the average IOP(15.5±1.1mmHg)in experimental group and the average IOP(19.7±2.5mmHg)in control group(P<0.05). Filtrative bleb: the incidence of the functional filtering bleb(86%)in experimental group was more than the one in control group(67%), there was significant different between the two groups(P<0.05). The incidence of complications of post-operation(shallow anterior chamber, choroidal detachment and bleb leaking)was lower than the one of the control group obviously. CONCLUSION: Combined trabeculectomy with bio-amnion implantation can increase the rate of success and reduce the incidence of complications.
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