Real-time magnetic actuation of DNA nanodevices via modular integration with stiff micro-levers

DNA molecular machines hold promise for biological nanotechnology, but how to actuate them in a fast and programmable manner remains challenging. Here, Lauback et al. demonstrate direct manipulation of DNA origami assemblies via a micrometer-long stiff mechanical lever controlled by a magnetic field...

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Main Authors:	Stephanie Lauback, Kara R. Mattioli, Alexander E. Marras, Maxim Armstrong, Thomas P. Rudibaugh, Ratnasingham Sooryakumar, Carlos E. Castro
Format:	Article
Language:	English
Published:	Nature Publishing Group 2018-04-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-018-03601-5

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spelling	doaj-12a5b4303f2c454cb20a60acd75c1dd52021-05-11T09:35:26ZengNature Publishing GroupNature Communications2041-17232018-04-019111110.1038/s41467-018-03601-5Real-time magnetic actuation of DNA nanodevices via modular integration with stiff micro-leversStephanie Lauback0Kara R. Mattioli1Alexander E. Marras2Maxim Armstrong3Thomas P. Rudibaugh4Ratnasingham Sooryakumar5Carlos E. Castro6Department of Physics, 191 W. Woodruff Ave, The Ohio State UniversityDepartment of Physics, 191 W. Woodruff Ave, The Ohio State UniversityDepartment of Mechanical & Aerospace Engineering, 201 W. 19th Ave, The Ohio State UniversityDepartment of Mechanical & Aerospace Engineering, 201 W. 19th Ave, The Ohio State UniversityDepartment of Chemical & Biomolecular Engineering, 151 W. Woodruff Ave, The Ohio State UniversityDepartment of Physics, 191 W. Woodruff Ave, The Ohio State UniversityDepartment of Mechanical & Aerospace Engineering, 201 W. 19th Ave, The Ohio State UniversityDNA molecular machines hold promise for biological nanotechnology, but how to actuate them in a fast and programmable manner remains challenging. Here, Lauback et al. demonstrate direct manipulation of DNA origami assemblies via a micrometer-long stiff mechanical lever controlled by a magnetic field.https://doi.org/10.1038/s41467-018-03601-5
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Stephanie Lauback Kara R. Mattioli Alexander E. Marras Maxim Armstrong Thomas P. Rudibaugh Ratnasingham Sooryakumar Carlos E. Castro
spellingShingle	Stephanie Lauback Kara R. Mattioli Alexander E. Marras Maxim Armstrong Thomas P. Rudibaugh Ratnasingham Sooryakumar Carlos E. Castro Real-time magnetic actuation of DNA nanodevices via modular integration with stiff micro-levers Nature Communications
author_facet	Stephanie Lauback Kara R. Mattioli Alexander E. Marras Maxim Armstrong Thomas P. Rudibaugh Ratnasingham Sooryakumar Carlos E. Castro
author_sort	Stephanie Lauback
title	Real-time magnetic actuation of DNA nanodevices via modular integration with stiff micro-levers
title_short	Real-time magnetic actuation of DNA nanodevices via modular integration with stiff micro-levers
title_full	Real-time magnetic actuation of DNA nanodevices via modular integration with stiff micro-levers
title_fullStr	Real-time magnetic actuation of DNA nanodevices via modular integration with stiff micro-levers
title_full_unstemmed	Real-time magnetic actuation of DNA nanodevices via modular integration with stiff micro-levers
title_sort	real-time magnetic actuation of dna nanodevices via modular integration with stiff micro-levers
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2018-04-01
description	DNA molecular machines hold promise for biological nanotechnology, but how to actuate them in a fast and programmable manner remains challenging. Here, Lauback et al. demonstrate direct manipulation of DNA origami assemblies via a micrometer-long stiff mechanical lever controlled by a magnetic field.
url	https://doi.org/10.1038/s41467-018-03601-5
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Real-time magnetic actuation of DNA nanodevices via modular integration with stiff micro-levers

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