Temperature and concentration calibration of aqueous polyvinylpyrrolidone (PVP) solutions for isotropic diffusion MRI phantoms.
To use the "apparent diffusion coefficient" (Dapp) as a quantitative imaging parameter, well-suited test fluids are essential. In this study, the previously proposed aqueous solutions of polyvinylpyrrolidone (PVP) were examined and temperature calibrations were obtained. For example, at a...
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doaj-12bd08a1c72740d185cf9ad0467d1ded2020-11-25T00:08:40ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01126e017927610.1371/journal.pone.0179276Temperature and concentration calibration of aqueous polyvinylpyrrolidone (PVP) solutions for isotropic diffusion MRI phantoms.Friedrich WagnerFrederik B LaunTristan A KuderAnna MlynarskaFlorian MaierJonas FaustKerstin DembergLinus LindemannBoris RivkinArmin M NagelMark E LaddKlaus Maier-HeinSebastian BickelhauptMichael BachTo use the "apparent diffusion coefficient" (Dapp) as a quantitative imaging parameter, well-suited test fluids are essential. In this study, the previously proposed aqueous solutions of polyvinylpyrrolidone (PVP) were examined and temperature calibrations were obtained. For example, at a temperature of 20°C, Dapp ranged from 1.594 (95% CI: 1.593, 1.595) μm2/ms to 0.3326 (95% CI: 0. 3304, 0.3348) μm2/ms for PVP-concentrations ranging from 10% (w/w) to 50% (w/w) using K30 polymer lengths. The temperature dependence of Dapp was found to be so strong that a negligence seems not advisable. The temperature dependence is descriptively modelled by an exponential function exp(c2 (T - 20°C)) and the determined c2 values are reported, which can be used for temperature calibration. For example, we find the value 0.02952 K-1 for 30% (w/w) PVP-concentration and K30 polymer length. In general, aqueous PVP solutions were found to be suitable to produce easily applicable and reliable Dapp-phantoms.http://europepmc.org/articles/PMC5476261?pdf=render |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Friedrich Wagner Frederik B Laun Tristan A Kuder Anna Mlynarska Florian Maier Jonas Faust Kerstin Demberg Linus Lindemann Boris Rivkin Armin M Nagel Mark E Ladd Klaus Maier-Hein Sebastian Bickelhaupt Michael Bach |
spellingShingle |
Friedrich Wagner Frederik B Laun Tristan A Kuder Anna Mlynarska Florian Maier Jonas Faust Kerstin Demberg Linus Lindemann Boris Rivkin Armin M Nagel Mark E Ladd Klaus Maier-Hein Sebastian Bickelhaupt Michael Bach Temperature and concentration calibration of aqueous polyvinylpyrrolidone (PVP) solutions for isotropic diffusion MRI phantoms. PLoS ONE |
author_facet |
Friedrich Wagner Frederik B Laun Tristan A Kuder Anna Mlynarska Florian Maier Jonas Faust Kerstin Demberg Linus Lindemann Boris Rivkin Armin M Nagel Mark E Ladd Klaus Maier-Hein Sebastian Bickelhaupt Michael Bach |
author_sort |
Friedrich Wagner |
title |
Temperature and concentration calibration of aqueous polyvinylpyrrolidone (PVP) solutions for isotropic diffusion MRI phantoms. |
title_short |
Temperature and concentration calibration of aqueous polyvinylpyrrolidone (PVP) solutions for isotropic diffusion MRI phantoms. |
title_full |
Temperature and concentration calibration of aqueous polyvinylpyrrolidone (PVP) solutions for isotropic diffusion MRI phantoms. |
title_fullStr |
Temperature and concentration calibration of aqueous polyvinylpyrrolidone (PVP) solutions for isotropic diffusion MRI phantoms. |
title_full_unstemmed |
Temperature and concentration calibration of aqueous polyvinylpyrrolidone (PVP) solutions for isotropic diffusion MRI phantoms. |
title_sort |
temperature and concentration calibration of aqueous polyvinylpyrrolidone (pvp) solutions for isotropic diffusion mri phantoms. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2017-01-01 |
description |
To use the "apparent diffusion coefficient" (Dapp) as a quantitative imaging parameter, well-suited test fluids are essential. In this study, the previously proposed aqueous solutions of polyvinylpyrrolidone (PVP) were examined and temperature calibrations were obtained. For example, at a temperature of 20°C, Dapp ranged from 1.594 (95% CI: 1.593, 1.595) μm2/ms to 0.3326 (95% CI: 0. 3304, 0.3348) μm2/ms for PVP-concentrations ranging from 10% (w/w) to 50% (w/w) using K30 polymer lengths. The temperature dependence of Dapp was found to be so strong that a negligence seems not advisable. The temperature dependence is descriptively modelled by an exponential function exp(c2 (T - 20°C)) and the determined c2 values are reported, which can be used for temperature calibration. For example, we find the value 0.02952 K-1 for 30% (w/w) PVP-concentration and K30 polymer length. In general, aqueous PVP solutions were found to be suitable to produce easily applicable and reliable Dapp-phantoms. |
url |
http://europepmc.org/articles/PMC5476261?pdf=render |
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