<i>Antrodia cinnamomea</i> Enhances Chemo-Sensitivity of 5-FU and Suppresses Colon Tumorigenesis and Cancer Stemness via Up-Regulation of Tumor Suppressor miR-142-3p

<i>Antrodia cinnamomea</i> Enhances Chemo-Sensitivity of 5-FU and Suppresses Colon Tumorigenesis and Cancer Stemness via Up-Regulation of Tumor Suppressor miR-142-3p

5-Fluorouracil (5-FU) regimen remains the backbone of the first-line agent to treat colon cancer, but often these patients develop resistance. Cancer stem cells (CSC&#8217;s) are considered as one of the key contributors in the development of drug resistance and tumor recurrence. We aimed to pro...

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Bibliographic Details
Main Authors: Yan-Jiun Huang, Vijesh Kumar Yadav, Prateeti Srivastava, Alexander TH Wu, Thanh-Tuan Huynh, Po-Li Wei, Chi-Ying F. Huang, Tse-Hung Huang
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Biomolecules
Subjects:
colon cancer
<i>AC</i>
5-FU
EMT
stemness
miR-142-3p
Online Access:https://www.mdpi.com/2218-273X/9/8/306

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