Functional Impact of Corticotropin-Releasing Factor Exposure on Tau Phosphorylation and Axon Transport.
Stress exposure or increased levels of corticotropin-releasing factor (CRF) induce hippocampal tau phosphorylation (tau-P) in rodent models, a process that is dependent on the type-1 CRF receptor (CRFR1). Although these preclinical studies on stress-induced tau-P provide mechanistic insight for epid...
Main Authors: | Michelle H Le, April M Weissmiller, Louise Monte, Po Han Lin, Tia C Hexom, Orlangie Natera, Chengbiao Wu, Robert A Rissman |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4720402?pdf=render |
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