Rethinking origin licensing

Rethinking origin licensing

Human cells that lack a subunit in their origin recognition complex are viable, which suggests the existence of alternative mechanisms to initiate DNA replication.

Bibliographic Details
Main Author: Stephen P Bell
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-01-01
Series:eLife
Subjects:
DNA replication
CDC6
ORC
MCM2-7
CDT1
Online Access:https://elifesciences.org/articles/24052
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spelling doaj-12c5dbab0d3744458ec3a2310d0b638d2021-05-05T13:12:09ZengeLife Sciences Publications LtdeLife2050-084X2017-01-01610.7554/eLife.24052Rethinking origin licensingStephen P Bell0https://orcid.org/0000-0002-2876-610XDepartment of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, United StatesHuman cells that lack a subunit in their origin recognition complex are viable, which suggests the existence of alternative mechanisms to initiate DNA replication.https://elifesciences.org/articles/24052DNA replicationCDC6ORCMCM2-7CDT1
collection DOAJ
language English
format Article
sources DOAJ
author Stephen P Bell
spellingShingle Stephen P Bell
Rethinking origin licensing
eLife
DNA replication
CDC6
ORC
MCM2-7
CDT1
author_facet Stephen P Bell
author_sort Stephen P Bell
title Rethinking origin licensing
title_short Rethinking origin licensing
title_full Rethinking origin licensing
title_fullStr Rethinking origin licensing
title_full_unstemmed Rethinking origin licensing
title_sort rethinking origin licensing
publisher eLife Sciences Publications Ltd
series eLife
issn 2050-084X
publishDate 2017-01-01
description Human cells that lack a subunit in their origin recognition complex are viable, which suggests the existence of alternative mechanisms to initiate DNA replication.
topic DNA replication
CDC6
ORC
MCM2-7
CDT1
url https://elifesciences.org/articles/24052
work_keys_str_mv AT stephenpbell rethinkingoriginlicensing
_version_ 1721462073212272640

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