Rethinking origin licensing
Human cells that lack a subunit in their origin recognition complex are viable, which suggests the existence of alternative mechanisms to initiate DNA replication.
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2017-01-01
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Online Access: | https://elifesciences.org/articles/24052 |
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doaj-12c5dbab0d3744458ec3a2310d0b638d2021-05-05T13:12:09ZengeLife Sciences Publications LtdeLife2050-084X2017-01-01610.7554/eLife.24052Rethinking origin licensingStephen P Bell0https://orcid.org/0000-0002-2876-610XDepartment of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, United StatesHuman cells that lack a subunit in their origin recognition complex are viable, which suggests the existence of alternative mechanisms to initiate DNA replication.https://elifesciences.org/articles/24052DNA replicationCDC6ORCMCM2-7CDT1 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Stephen P Bell |
spellingShingle |
Stephen P Bell Rethinking origin licensing eLife DNA replication CDC6 ORC MCM2-7 CDT1 |
author_facet |
Stephen P Bell |
author_sort |
Stephen P Bell |
title |
Rethinking origin licensing |
title_short |
Rethinking origin licensing |
title_full |
Rethinking origin licensing |
title_fullStr |
Rethinking origin licensing |
title_full_unstemmed |
Rethinking origin licensing |
title_sort |
rethinking origin licensing |
publisher |
eLife Sciences Publications Ltd |
series |
eLife |
issn |
2050-084X |
publishDate |
2017-01-01 |
description |
Human cells that lack a subunit in their origin recognition complex are viable, which suggests the existence of alternative mechanisms to initiate DNA replication. |
topic |
DNA replication CDC6 ORC MCM2-7 CDT1 |
url |
https://elifesciences.org/articles/24052 |
work_keys_str_mv |
AT stephenpbell rethinkingoriginlicensing |
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