Tolerogenic IDO+ dendritic cells are induced by PD-1-expressing mast cells

Tolerogenic IDO+ dendritic cells are induced by PD-1-expressing mast cells

Mast cells (MC) are tissue resident cells, rich in inflammatory mediators, involved in allergic reactions, and with an increasingly recognized role in immunomodulation. Dendritic cells (DCs), on the other hand, are central to the determination of immune response patterns, being highly efficient anti...

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Bibliographic Details
Main Authors: Cecilia Pessoa Rodrigues, Ana Carolina Franco Ferreira, Mariana Pereira Pinho, Cristiano Jacob de Moraes, Patrícia Cruz Bergami-Santos, Jose Alexandre Marzagao Barbuto
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Immunology
Subjects:
Mast Cells
IDO
STAT-3
Tregs
tolerogenic DCs
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00009/full

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