PAEDIATRIC DESMOPLASTIC MEDULLOBLASTOMA – SURGICAL TREATMENT, ADJUVANT THERAPY, OUTCOME SURVIVAL (CASE SERIES STUDY)
background. Desmoplastic medulloblastoma is a common adult cerebellar tumor. It has better than classic medulloblastoma outcome. This is a case series study followed up the cases of paediatric desmoplastic medulloblastoma and their treatment outcome and prognosis. Aim of study. Evaluation of the ma...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Amaltea Medical Publishing House
2020-03-01
|
Series: | Romanian Journal of Neurology |
Subjects: | |
Online Access: | https://rjn.com.ro/articles/2020.1/RJN_2020_1_Art-07.pdf |
id |
doaj-12e5794ec3864776bb6a805ce4e2bdfa |
---|---|
record_format |
Article |
spelling |
doaj-12e5794ec3864776bb6a805ce4e2bdfa2021-07-28T14:34:53ZengAmaltea Medical Publishing HouseRomanian Journal of Neurology1843-81482069-60942020-03-01191465310.37897/RJN.2020.1.7PAEDIATRIC DESMOPLASTIC MEDULLOBLASTOMA – SURGICAL TREATMENT, ADJUVANT THERAPY, OUTCOME SURVIVAL (CASE SERIES STUDY)Raad Ahmed HUSSEIN0Muhammed Hameed FAEADH AL-JUMAILY1Rana Hani Mohammed Ali AL-SHAIKH HAMED2Asaad F. ALBAYATI3Department of Internal Medicine, Neurology Unit, College of Medicine, Aliraqia University, Baghdad, IraqDepartment of Surgery, College of Medicine, Aliraqia University, Baghdad, IraqDepartment of Pharmacology, College of Medicine, Aliraqia University, Baghdad, IraqDepartment of Pathology, College of Medicine, Aliraqia University, Baghdad, Iraqbackground. Desmoplastic medulloblastoma is a common adult cerebellar tumor. It has better than classic medulloblastoma outcome. This is a case series study followed up the cases of paediatric desmoplastic medulloblastoma and their treatment outcome and prognosis. Aim of study. Evaluation of the management and outcome survival, of this uncommon paediatric desmoplastic variety of medulloblastoma. Methods. 20 paediatric patients of desmoplastic medulloblastoma were collected between 2008 and 2017; 12 were males and 8 were females. All the cases were treated firstly for hydrocephalus followed by craniotomy and tumor resection. results. The children were treated medically and surgically; the desmoplastic variant of medulloblastoma demonstrated better than classic medulloblastoma outcome. Median follow-up was 24 months. The younger the child, the better the outcome. 4 patients died from recurrent medulloblastoma. Bad outcomes were in recurrent and disseminated medulloblastomas. conclusions. Surgical resection followed by chemotherapy and/or radiotherapy give better outcome in desmoplastic medulloblastoma patients comparing with the classical medulloblastoma. https://rjn.com.ro/articles/2020.1/RJN_2020_1_Art-07.pdfmedulloblastomadesmoplastic medulloblastomachildren |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Raad Ahmed HUSSEIN Muhammed Hameed FAEADH AL-JUMAILY Rana Hani Mohammed Ali AL-SHAIKH HAMED Asaad F. ALBAYATI |
spellingShingle |
Raad Ahmed HUSSEIN Muhammed Hameed FAEADH AL-JUMAILY Rana Hani Mohammed Ali AL-SHAIKH HAMED Asaad F. ALBAYATI PAEDIATRIC DESMOPLASTIC MEDULLOBLASTOMA – SURGICAL TREATMENT, ADJUVANT THERAPY, OUTCOME SURVIVAL (CASE SERIES STUDY) Romanian Journal of Neurology medulloblastoma desmoplastic medulloblastoma children |
author_facet |
Raad Ahmed HUSSEIN Muhammed Hameed FAEADH AL-JUMAILY Rana Hani Mohammed Ali AL-SHAIKH HAMED Asaad F. ALBAYATI |
author_sort |
Raad Ahmed HUSSEIN |
title |
PAEDIATRIC DESMOPLASTIC MEDULLOBLASTOMA – SURGICAL TREATMENT, ADJUVANT THERAPY, OUTCOME SURVIVAL (CASE SERIES STUDY) |
title_short |
PAEDIATRIC DESMOPLASTIC MEDULLOBLASTOMA – SURGICAL TREATMENT, ADJUVANT THERAPY, OUTCOME SURVIVAL (CASE SERIES STUDY) |
title_full |
PAEDIATRIC DESMOPLASTIC MEDULLOBLASTOMA – SURGICAL TREATMENT, ADJUVANT THERAPY, OUTCOME SURVIVAL (CASE SERIES STUDY) |
title_fullStr |
PAEDIATRIC DESMOPLASTIC MEDULLOBLASTOMA – SURGICAL TREATMENT, ADJUVANT THERAPY, OUTCOME SURVIVAL (CASE SERIES STUDY) |
title_full_unstemmed |
PAEDIATRIC DESMOPLASTIC MEDULLOBLASTOMA – SURGICAL TREATMENT, ADJUVANT THERAPY, OUTCOME SURVIVAL (CASE SERIES STUDY) |
title_sort |
paediatric desmoplastic medulloblastoma – surgical treatment, adjuvant therapy, outcome survival (case series study) |
publisher |
Amaltea Medical Publishing House |
series |
Romanian Journal of Neurology |
issn |
1843-8148 2069-6094 |
publishDate |
2020-03-01 |
description |
background. Desmoplastic medulloblastoma is a common adult cerebellar tumor. It has better than classic medulloblastoma outcome. This is a case series study followed up the cases of paediatric desmoplastic medulloblastoma and their treatment outcome and prognosis.
Aim of study. Evaluation of the management and outcome survival, of this uncommon paediatric desmoplastic variety of medulloblastoma.
Methods. 20 paediatric patients of desmoplastic medulloblastoma were collected between 2008 and 2017; 12 were males and 8 were females. All the cases were treated firstly for hydrocephalus followed by craniotomy and tumor resection. results. The children were treated medically and surgically; the desmoplastic variant of medulloblastoma demonstrated better than classic medulloblastoma outcome. Median follow-up was 24 months. The younger the child, the better the outcome. 4 patients died from recurrent medulloblastoma. Bad outcomes were in recurrent and disseminated medulloblastomas. conclusions. Surgical resection followed by chemotherapy and/or radiotherapy give better outcome in desmoplastic
medulloblastoma patients comparing with the classical medulloblastoma. |
topic |
medulloblastoma desmoplastic medulloblastoma children |
url |
https://rjn.com.ro/articles/2020.1/RJN_2020_1_Art-07.pdf |
work_keys_str_mv |
AT raadahmedhussein paediatricdesmoplasticmedulloblastomasurgicaltreatmentadjuvanttherapyoutcomesurvivalcaseseriesstudy AT muhammedhameedfaeadhaljumaily paediatricdesmoplasticmedulloblastomasurgicaltreatmentadjuvanttherapyoutcomesurvivalcaseseriesstudy AT ranahanimohammedalialshaikhhamed paediatricdesmoplasticmedulloblastomasurgicaltreatmentadjuvanttherapyoutcomesurvivalcaseseriesstudy AT asaadfalbayati paediatricdesmoplasticmedulloblastomasurgicaltreatmentadjuvanttherapyoutcomesurvivalcaseseriesstudy |
_version_ |
1721268132352360448 |