Prevalence of Mutations in the <i>pfcoronin</i> Gene and Association with Ex Vivo Susceptibility to Common Quinoline Drugs against <i>Plasmodium falciparum</i>

Prevalence of Mutations in the <i>pfcoronin</i> Gene and Association with Ex Vivo Susceptibility to Common Quinoline Drugs against <i>Plasmodium falciparum</i>

Background: Artemisinin-based combination therapy (ACT) was recommended to treat uncomplicated falciparum malaria. Unlike the situation in Asia where resistance to ACT has been reported, artemisinin resistance has not yet emerged in Africa. However, some rare failures with ACT or patients continuing...

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Bibliographic Details
Main Authors: Océane Delandre, Mathieu Gendrot, Isabelle Fonta, Joel Mosnier, Nicolas Benoit, Rémy Amalvict, Nicolas Gomez, Marylin Madamet, Bruno Pradines
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceutics
Subjects:
malaria
<i>Plasmodium falciparum</i>
antimalarial drug
<i>pfcoronin</i>
resistance
in vitro
Online Access:https://www.mdpi.com/1999-4923/13/8/1273

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