Gene Expression Profile in Immortalized Human Periodontal Ligament Fibroblasts Through hTERT Ectopic Expression: Transcriptome and Bioinformatic Analysis

Gene Expression Profile in Immortalized Human Periodontal Ligament Fibroblasts Through hTERT Ectopic Expression: Transcriptome and Bioinformatic Analysis

Human periodontal ligament fibroblast (hPLF) cells play an important role in maintaining oral cavity homeostasis with special function in tissue regeneration and maintenance of dental alveoli. Although their primary cell cultures are considered a good experimental model with no genetic changes, the...

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Bibliographic Details
Main Authors: Lygia S. Nogueira, Carolina P. Vasconcelos, Geovanni Pereira Mitre, Leonardo Oliveira Bittencourt, Jessica Rodrigues Plaça, Maria Sueli da Silva Kataoka, João de Jesus Viana Pinheiro, Gustavo Pompermaier Garlet, Edivaldo H. C. De Oliveira, Rafael R. Lima
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
S100A7
cell culture
periodontal fibroblast
immortalization
hTERT
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.679548/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.679548/full

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