Bartonella henselae DNA in Seronegative Patients with Cat-Scratch Disease

We used real-time PCR to detect Bartonella henselae DNA in 7.9% (5/63) of blood specimens from seronegative patients in Japan suspected of having cat-scratch disease. The combined use of serologic tests and real-time PCR to analyze blood specimens is recommended for the prompt, noninvasive laborator...

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Main Authors: Masashi Yanagihara, Hidehiro Tsuneoka, Ayano Tanimoto, Ken-ichiro Otsuyama, Jun Nishikawa, Tomohiro Matsui, Junzo Nojima, Kiyoshi Ichihara
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2018-05-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/24/5/15-2033_article
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spelling doaj-13111fa86541414d983f0829df0fab732020-11-24T21:50:07ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592018-05-0124592492510.3201/eid2405.152033Bartonella henselae DNA in Seronegative Patients with Cat-Scratch DiseaseMasashi YanagiharaHidehiro TsuneokaAyano TanimotoKen-ichiro OtsuyamaJun NishikawaTomohiro MatsuiJunzo NojimaKiyoshi IchiharaWe used real-time PCR to detect Bartonella henselae DNA in 7.9% (5/63) of blood specimens from seronegative patients in Japan suspected of having cat-scratch disease. The combined use of serologic tests and real-time PCR to analyze blood specimens is recommended for the prompt, noninvasive laboratory diagnosis of cat-scratch disease.https://wwwnc.cdc.gov/eid/article/24/5/15-2033_articleCat-scratch diseaseBartonella henselaeperipheral bloodreal-time PCRindirect fluorescence antibody assayJapan
collection DOAJ
language English
format Article
sources DOAJ
author Masashi Yanagihara
Hidehiro Tsuneoka
Ayano Tanimoto
Ken-ichiro Otsuyama
Jun Nishikawa
Tomohiro Matsui
Junzo Nojima
Kiyoshi Ichihara
spellingShingle Masashi Yanagihara
Hidehiro Tsuneoka
Ayano Tanimoto
Ken-ichiro Otsuyama
Jun Nishikawa
Tomohiro Matsui
Junzo Nojima
Kiyoshi Ichihara
Bartonella henselae DNA in Seronegative Patients with Cat-Scratch Disease
Emerging Infectious Diseases
Cat-scratch disease
Bartonella henselae
peripheral blood
real-time PCR
indirect fluorescence antibody assay
Japan
author_facet Masashi Yanagihara
Hidehiro Tsuneoka
Ayano Tanimoto
Ken-ichiro Otsuyama
Jun Nishikawa
Tomohiro Matsui
Junzo Nojima
Kiyoshi Ichihara
author_sort Masashi Yanagihara
title Bartonella henselae DNA in Seronegative Patients with Cat-Scratch Disease
title_short Bartonella henselae DNA in Seronegative Patients with Cat-Scratch Disease
title_full Bartonella henselae DNA in Seronegative Patients with Cat-Scratch Disease
title_fullStr Bartonella henselae DNA in Seronegative Patients with Cat-Scratch Disease
title_full_unstemmed Bartonella henselae DNA in Seronegative Patients with Cat-Scratch Disease
title_sort bartonella henselae dna in seronegative patients with cat-scratch disease
publisher Centers for Disease Control and Prevention
series Emerging Infectious Diseases
issn 1080-6040
1080-6059
publishDate 2018-05-01
description We used real-time PCR to detect Bartonella henselae DNA in 7.9% (5/63) of blood specimens from seronegative patients in Japan suspected of having cat-scratch disease. The combined use of serologic tests and real-time PCR to analyze blood specimens is recommended for the prompt, noninvasive laboratory diagnosis of cat-scratch disease.
topic Cat-scratch disease
Bartonella henselae
peripheral blood
real-time PCR
indirect fluorescence antibody assay
Japan
url https://wwwnc.cdc.gov/eid/article/24/5/15-2033_article
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