Immunosenescence and Its Hallmarks: How to Oppose Aging Strategically? A Review of Potential Options for Therapeutic Intervention
Aging is accompanied by remodeling of the immune system. With time, this leads to a decline in immune efficacy, resulting in increased vulnerability to infectious diseases, diminished responses to vaccination, and a susceptibility to age-related inflammatory diseases. An age-associated immune altera...
Main Authors: | Anna Aiello, Farzin Farzaneh, Giuseppina Candore, Calogero Caruso, Sergio Davinelli, Caterina Maria Gambino, Mattia Emanuela Ligotti, Nahid Zareian, Giulia Accardi |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-09-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fimmu.2019.02247/full |
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