Classic Antiphospholipid and Antiphosphatidylserine Antibody Profile in Suspected Antiphospholipid Antibody Syndrome Patient
Objective: To compare the classic examination results of antiphospholipid (aPS) and antiphospatidylserine (aPL) antibody profile to establish the diagnosis from suspected antiphospholipid antibody syndrome (APS) patient in order to state the subsequent treatment strategies. Method: This descr...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Indonesian Society of Obstetrics and Gynecology
2016-07-01
|
Series: | Indonesian Journal of Obstetrics and Gynecology |
Online Access: | http://inajog.com/index.php/journal/article/view/435 |
id |
doaj-1314c741a5f445c4a41da27b4a6dd24d |
---|---|
record_format |
Article |
spelling |
doaj-1314c741a5f445c4a41da27b4a6dd24d2021-06-02T03:56:17ZengIndonesian Society of Obstetrics and GynecologyIndonesian Journal of Obstetrics and Gynecology2338-64012338-73352016-07-0113814110.32771/inajog.v4i3.435435Classic Antiphospholipid and Antiphosphatidylserine Antibody Profile in Suspected Antiphospholipid Antibody Syndrome PatientAngga J Suryadi0Kanadi Sumapradja1Faculty of Medicine Universitas Indonesia/ Dr. Cipto Mangunkusumo Hospital JakartaFaculty of Medicine Universitas Indonesia/ Dr. Cipto Mangunkusumo Hospital JakartaObjective: To compare the classic examination results of antiphospholipid (aPS) and antiphospatidylserine (aPL) antibody profile to establish the diagnosis from suspected antiphospholipid antibody syndrome (APS) patient in order to state the subsequent treatment strategies. Method: This descriptive cross-sectional study design was conducted at outpatient clinics of Dr. Cipto Mangunkusumo Hospital (RSCM) from January to December 2015. The laboratory test was held in Clinical Pathology Laboratory RSCM/Faculty of Medicine Universitas Indonesia (FKUI) and in corporation with Prodia laboratory. Result: All of normal patients did not have positive result in any laboratory examination (Lupus Anti-coagulant (LA), anticardiolipin (aCL), anti-?2 glycoprotein I (anti-?2GPI), and aPS). In patient suspected APS, 11 (37.1%) patients had positive aCL, 7 (25.9%) patients had positive anti-?2GPI, and 11 (37.1%) patients had positive aPS. The most positive cross laboratory examination was between aCL and aPS (25.9%). In this study, we found the most positive test result was aCL and aPS (62.9%). From this study, suspected APS patient who had negative result in classic laboratory examination, but showing the positive result in aPS was in 5 (18.5%) patients. Conclusion: All normal pregnant patients do not have any positive classic examination and aPS. Meanwhile, in patients with suspected APS, less than 20% patients show positive result of aPS with negative result in classic laboratory examination. Keywords: antiphospatidylserine, antiphospolipid syndromehttp://inajog.com/index.php/journal/article/view/435 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Angga J Suryadi Kanadi Sumapradja |
spellingShingle |
Angga J Suryadi Kanadi Sumapradja Classic Antiphospholipid and Antiphosphatidylserine Antibody Profile in Suspected Antiphospholipid Antibody Syndrome Patient Indonesian Journal of Obstetrics and Gynecology |
author_facet |
Angga J Suryadi Kanadi Sumapradja |
author_sort |
Angga J Suryadi |
title |
Classic Antiphospholipid and Antiphosphatidylserine Antibody Profile in Suspected Antiphospholipid Antibody Syndrome Patient |
title_short |
Classic Antiphospholipid and Antiphosphatidylserine Antibody Profile in Suspected Antiphospholipid Antibody Syndrome Patient |
title_full |
Classic Antiphospholipid and Antiphosphatidylserine Antibody Profile in Suspected Antiphospholipid Antibody Syndrome Patient |
title_fullStr |
Classic Antiphospholipid and Antiphosphatidylserine Antibody Profile in Suspected Antiphospholipid Antibody Syndrome Patient |
title_full_unstemmed |
Classic Antiphospholipid and Antiphosphatidylserine Antibody Profile in Suspected Antiphospholipid Antibody Syndrome Patient |
title_sort |
classic antiphospholipid and antiphosphatidylserine antibody profile in suspected antiphospholipid antibody syndrome patient |
publisher |
Indonesian Society of Obstetrics and Gynecology |
series |
Indonesian Journal of Obstetrics and Gynecology |
issn |
2338-6401 2338-7335 |
publishDate |
2016-07-01 |
description |
Objective: To compare the classic examination results of antiphospholipid
(aPS) and antiphospatidylserine (aPL) antibody profile to
establish the diagnosis from suspected antiphospholipid antibody
syndrome (APS) patient in order to state the subsequent treatment
strategies.
Method: This descriptive cross-sectional study design was conducted
at outpatient clinics of Dr. Cipto Mangunkusumo Hospital
(RSCM) from January to December 2015. The laboratory test was
held in Clinical Pathology Laboratory RSCM/Faculty of Medicine
Universitas Indonesia (FKUI) and in corporation with Prodia laboratory.
Result: All of normal patients did not have positive result in any
laboratory examination (Lupus Anti-coagulant (LA), anticardiolipin
(aCL), anti-?2 glycoprotein I (anti-?2GPI), and aPS). In patient suspected
APS, 11 (37.1%) patients had positive aCL, 7 (25.9%) patients
had positive anti-?2GPI, and 11 (37.1%) patients had positive
aPS. The most positive cross laboratory examination was between
aCL and aPS (25.9%). In this study, we found the most positive test
result was aCL and aPS (62.9%). From this study, suspected APS patient
who had negative result in classic laboratory examination, but
showing the positive result in aPS was in 5 (18.5%) patients.
Conclusion: All normal pregnant patients do not have any positive
classic examination and aPS. Meanwhile, in patients with suspected
APS, less than 20% patients show positive result of aPS with negative
result in classic laboratory examination.
Keywords: antiphospatidylserine, antiphospolipid syndrome |
url |
http://inajog.com/index.php/journal/article/view/435 |
work_keys_str_mv |
AT anggajsuryadi classicantiphospholipidandantiphosphatidylserineantibodyprofileinsuspectedantiphospholipidantibodysyndromepatient AT kanadisumapradja classicantiphospholipidandantiphosphatidylserineantibodyprofileinsuspectedantiphospholipidantibodysyndromepatient |
_version_ |
1721408691477938176 |