B7-H3 as a Novel CAR-T Therapeutic Target for Glioblastoma

Glioblastoma (GBM) remains one of the most malignant primary tumors in adults, with a 5-year survival rate less than 10% because of lacking effective treatment. Here, we aimed to explore whether B7-H3 could serve as a novel therapeutic target for GBM in chimeric antigen receptor (CAR) T cell therapy...

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Bibliographic Details
Main Authors: Xin Tang, Shasha Zhao, Yang Zhang, Yuelong Wang, Zongliang Zhang, Meijia Yang, Yanyu Zhu, Guanjie Zhang, Gang Guo, Aiping Tong, Liangxue Zhou
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770519300683