A Potential Role for MMPs during the Formation of Non-Neurogenic Placodes

The formation of non-neurogenic placodes is critical prior to the development of several epithelial derivatives (e.g., feathers, teeth, etc.) and their development frequently involves morphogenetic proteins (or morphogens). Matrix metalloproteinases (MMPs) are important enzymes involved in extracell...

Full description

Bibliographic Details
Main Authors:	Paige M. Drake, Tamara A. Franz-Odendaal
Format:	Article
Language:	English
Published:	MDPI AG 2018-07-01
Series:	Journal of Developmental Biology
Subjects:	extracellular matrix morphogens embryo matrix metalloproteases tooth lens mammary gland feather hair β-catenin patterning
Online Access:	http://www.mdpi.com/2221-3759/6/3/20

id	doaj-1351fd7b5fef401686205c573e0d7521
record_format	Article
spelling	doaj-1351fd7b5fef401686205c573e0d75212020-11-24T23:11:07ZengMDPI AGJournal of Developmental Biology2221-37592018-07-01632010.3390/jdb6030020jdb6030020A Potential Role for MMPs during the Formation of Non-Neurogenic PlacodesPaige M. Drake0Tamara A. Franz-Odendaal1Department of Medical Neuroscience, Dalhousie University, 5850 College Street, Halifax, NS B3H 4R2, CanadaDepartment of Medical Neuroscience, Dalhousie University, 5850 College Street, Halifax, NS B3H 4R2, CanadaThe formation of non-neurogenic placodes is critical prior to the development of several epithelial derivatives (e.g., feathers, teeth, etc.) and their development frequently involves morphogenetic proteins (or morphogens). Matrix metalloproteinases (MMPs) are important enzymes involved in extracellular matrix remodeling, and recent research has shown that the extracellular matrix (ECM) can modulate morphogen diffusion and cell behaviors. This review summarizes the known roles of MMPs during the development of non-neurogenic structures that involve a placodal stage. Specifically, we discuss feather, hair, tooth, mammary gland and lens development. This review highlights the potential critical role MMPs may play during placode formation in these systems.http://www.mdpi.com/2221-3759/6/3/20extracellular matrixmorphogensembryomatrix metalloproteasestoothlensmammary glandfeatherhairβ-cateninpatterning
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Paige M. Drake Tamara A. Franz-Odendaal
spellingShingle	Paige M. Drake Tamara A. Franz-Odendaal A Potential Role for MMPs during the Formation of Non-Neurogenic Placodes Journal of Developmental Biology extracellular matrix morphogens embryo matrix metalloproteases tooth lens mammary gland feather hair β-catenin patterning
author_facet	Paige M. Drake Tamara A. Franz-Odendaal
author_sort	Paige M. Drake
title	A Potential Role for MMPs during the Formation of Non-Neurogenic Placodes
title_short	A Potential Role for MMPs during the Formation of Non-Neurogenic Placodes
title_full	A Potential Role for MMPs during the Formation of Non-Neurogenic Placodes
title_fullStr	A Potential Role for MMPs during the Formation of Non-Neurogenic Placodes
title_full_unstemmed	A Potential Role for MMPs during the Formation of Non-Neurogenic Placodes
title_sort	potential role for mmps during the formation of non-neurogenic placodes
publisher	MDPI AG
series	Journal of Developmental Biology
issn	2221-3759
publishDate	2018-07-01
description	The formation of non-neurogenic placodes is critical prior to the development of several epithelial derivatives (e.g., feathers, teeth, etc.) and their development frequently involves morphogenetic proteins (or morphogens). Matrix metalloproteinases (MMPs) are important enzymes involved in extracellular matrix remodeling, and recent research has shown that the extracellular matrix (ECM) can modulate morphogen diffusion and cell behaviors. This review summarizes the known roles of MMPs during the development of non-neurogenic structures that involve a placodal stage. Specifically, we discuss feather, hair, tooth, mammary gland and lens development. This review highlights the potential critical role MMPs may play during placode formation in these systems.
topic	extracellular matrix morphogens embryo matrix metalloproteases tooth lens mammary gland feather hair β-catenin patterning
url	http://www.mdpi.com/2221-3759/6/3/20
work_keys_str_mv	AT paigemdrake apotentialroleformmpsduringtheformationofnonneurogenicplacodes AT tamaraafranzodendaal apotentialroleformmpsduringtheformationofnonneurogenicplacodes AT paigemdrake potentialroleformmpsduringtheformationofnonneurogenicplacodes AT tamaraafranzodendaal potentialroleformmpsduringtheformationofnonneurogenicplacodes
_version_	1725605573765890048

A Potential Role for MMPs during the Formation of Non-Neurogenic Placodes

Similar Items