The value of systematic pattern analysis in FNAC of breast lesions: 225 cases with cytohistological correlation
Background : Fine needle aspiration cytology (FNAC) has a high rating in the assessment of breast lesions. Various methods have been used to diagnose cytology of breast lesions. Aims : Present study was undertaken to evaluate the feasibility of application of systematic pattern analysis based on m...
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doaj-13699163e05a4b15a5a3725e42d719b02020-11-24T23:20:51ZengWolters Kluwer Medknow PublicationsJournal of Cytology0970-93712011-01-01281131910.4103/0970-9371.76942The value of systematic pattern analysis in FNAC of breast lesions: 225 cases with cytohistological correlationPrakash H MuddegowdaJyothi B LingegowdaRamkumar KurpadP G KonapurA S ShivarudrappaP M SubramaniamBackground : Fine needle aspiration cytology (FNAC) has a high rating in the assessment of breast lesions. Various methods have been used to diagnose cytology of breast lesions. Aims : Present study was undertaken to evaluate the feasibility of application of systematic pattern analysis based on morphology in diagnosing breast aspirates. Materials and Methods : This is a retrospective study of FNAC of the breast done over a period of 4 years in a tertiary care centre. A total of 225 cases of breast lesions for which FNAC was done with histological follow-up were included in the study. Breast aspirates were provisionally diagnosed based on systematic pattern analysis. Aspirates were grouped into six categories based on predominant cellular pattern, and correlation between cytological and histological diagnosis was assessed. Results : Application of pattern analysis on FNAC of breast lesions in our study had a sensitivity of 94.5%, specificity of 98%, diagnostic accuracy of 97%, positive predictive value of 95.8%, and negative predictive value of 97.4%. Conclusions : Systematic pattern analysis based on morphology of FNAC smears was found to be highly reliable and could be easily reproducible in the assessment of breast masses.http://www.jcytol.org/article.asp?issn=0970-9371;year=2011;volume=28;issue=1;spage=13;epage=19;aulast=MuddegowdaBreast lumps; fine needle aspiration cytology; histopathology; pattern analysis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Prakash H Muddegowda Jyothi B Lingegowda Ramkumar Kurpad P G Konapur A S Shivarudrappa P M Subramaniam |
spellingShingle |
Prakash H Muddegowda Jyothi B Lingegowda Ramkumar Kurpad P G Konapur A S Shivarudrappa P M Subramaniam The value of systematic pattern analysis in FNAC of breast lesions: 225 cases with cytohistological correlation Journal of Cytology Breast lumps; fine needle aspiration cytology; histopathology; pattern analysis |
author_facet |
Prakash H Muddegowda Jyothi B Lingegowda Ramkumar Kurpad P G Konapur A S Shivarudrappa P M Subramaniam |
author_sort |
Prakash H Muddegowda |
title |
The value of systematic pattern analysis in FNAC of breast lesions: 225 cases with cytohistological correlation |
title_short |
The value of systematic pattern analysis in FNAC of breast lesions: 225 cases with cytohistological correlation |
title_full |
The value of systematic pattern analysis in FNAC of breast lesions: 225 cases with cytohistological correlation |
title_fullStr |
The value of systematic pattern analysis in FNAC of breast lesions: 225 cases with cytohistological correlation |
title_full_unstemmed |
The value of systematic pattern analysis in FNAC of breast lesions: 225 cases with cytohistological correlation |
title_sort |
value of systematic pattern analysis in fnac of breast lesions: 225 cases with cytohistological correlation |
publisher |
Wolters Kluwer Medknow Publications |
series |
Journal of Cytology |
issn |
0970-9371 |
publishDate |
2011-01-01 |
description |
Background : Fine needle aspiration cytology (FNAC) has a high rating in the assessment of breast lesions. Various methods have been used to diagnose cytology of breast lesions.
Aims : Present study was undertaken to evaluate the feasibility of application of systematic pattern analysis based on morphology in diagnosing breast aspirates.
Materials and Methods : This is a retrospective study of FNAC of the breast done over a period of 4 years in a tertiary care centre. A total of 225 cases of breast lesions for which FNAC was done with histological follow-up were included in the study. Breast aspirates were provisionally diagnosed based on systematic pattern analysis. Aspirates were grouped into six categories based on predominant cellular pattern, and correlation between cytological and histological diagnosis was assessed.
Results : Application of pattern analysis on FNAC of breast lesions in our study had a sensitivity of 94.5%, specificity of 98%, diagnostic accuracy of 97%, positive predictive value of 95.8%, and negative predictive value of 97.4%.
Conclusions : Systematic pattern analysis based on morphology of FNAC smears was found to be highly reliable and could be easily reproducible in the assessment of breast masses. |
topic |
Breast lumps; fine needle aspiration cytology; histopathology; pattern analysis |
url |
http://www.jcytol.org/article.asp?issn=0970-9371;year=2011;volume=28;issue=1;spage=13;epage=19;aulast=Muddegowda |
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