Ordinary and Activated Bone Grafts: Applied Classification and the Main Features
Bone grafts are medical devices that are in high demand in clinical practice for substitution of bone defects and recovery of atrophic bone regions. Based on the analysis of the modern groups of bone grafts, the particularities of their composition, the mechanisms of their biological effects, and th...
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2015/365050 |
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doaj-136b020c2e0c48d2a9c55bbadb9cc1c72020-11-25T00:06:59ZengHindawi LimitedBioMed Research International2314-61332314-61412015-01-01201510.1155/2015/365050365050Ordinary and Activated Bone Grafts: Applied Classification and the Main FeaturesR. V. Deev0A. Y. Drobyshev1I. Y. Bozo2A. A. Isaev3Human Stem Cells Institute, Moscow 199333, RussiaDepartment of Maxillofacial and Plastic Surgery, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow 127473, RussiaHuman Stem Cells Institute, Moscow 199333, RussiaHuman Stem Cells Institute, Moscow 199333, RussiaBone grafts are medical devices that are in high demand in clinical practice for substitution of bone defects and recovery of atrophic bone regions. Based on the analysis of the modern groups of bone grafts, the particularities of their composition, the mechanisms of their biological effects, and their therapeutic indications, applicable classification was proposed that separates the bone substitutes into “ordinary” and “activated.” The main differential criterion is the presence of biologically active components in the material that are standardized by qualitative and quantitative parameters: growth factors, cells, or gene constructions encoding growth factors. The pronounced osteoinductive and (or) osteogenic properties of activated osteoplastic materials allow drawing upon their efficacy in the substitution of large bone defects.http://dx.doi.org/10.1155/2015/365050 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
R. V. Deev A. Y. Drobyshev I. Y. Bozo A. A. Isaev |
spellingShingle |
R. V. Deev A. Y. Drobyshev I. Y. Bozo A. A. Isaev Ordinary and Activated Bone Grafts: Applied Classification and the Main Features BioMed Research International |
author_facet |
R. V. Deev A. Y. Drobyshev I. Y. Bozo A. A. Isaev |
author_sort |
R. V. Deev |
title |
Ordinary and Activated Bone Grafts: Applied Classification and the Main Features |
title_short |
Ordinary and Activated Bone Grafts: Applied Classification and the Main Features |
title_full |
Ordinary and Activated Bone Grafts: Applied Classification and the Main Features |
title_fullStr |
Ordinary and Activated Bone Grafts: Applied Classification and the Main Features |
title_full_unstemmed |
Ordinary and Activated Bone Grafts: Applied Classification and the Main Features |
title_sort |
ordinary and activated bone grafts: applied classification and the main features |
publisher |
Hindawi Limited |
series |
BioMed Research International |
issn |
2314-6133 2314-6141 |
publishDate |
2015-01-01 |
description |
Bone grafts are medical devices that are in high demand in clinical practice for substitution of bone defects and recovery of atrophic bone regions. Based on the analysis of the modern groups of bone grafts, the particularities of their composition, the mechanisms of their biological effects, and their therapeutic indications, applicable classification was proposed that separates the bone substitutes into “ordinary” and “activated.” The main differential criterion is the presence of biologically active components in the material that are standardized by qualitative and quantitative parameters: growth factors, cells, or gene constructions encoding growth factors. The pronounced osteoinductive and (or) osteogenic properties of activated osteoplastic materials allow drawing upon their efficacy in the substitution of large bone defects. |
url |
http://dx.doi.org/10.1155/2015/365050 |
work_keys_str_mv |
AT rvdeev ordinaryandactivatedbonegraftsappliedclassificationandthemainfeatures AT aydrobyshev ordinaryandactivatedbonegraftsappliedclassificationandthemainfeatures AT iybozo ordinaryandactivatedbonegraftsappliedclassificationandthemainfeatures AT aaisaev ordinaryandactivatedbonegraftsappliedclassificationandthemainfeatures |
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1725420563679150080 |