Radiologic Complete Response In Lung Adenocarcinoma With Symptomatic Brain Metastasis After Systematic Therapy: A Case Study
Jianxin Chen,1 Junhui Wang,2 Qinhong Zheng,1 Meiling Weng,1 Xilin Wu1 1Department of Medical Oncology, Quzhou People’s Hospital, Quzhou, Zhejiang 324000, People’s Republic of China; 2Department of Radiation Oncology, Quzhou People’s Hospital, Quzhou, Zhejiang 324000, Pe...
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doaj-136d1069a3a7476e8528154909d72f492020-11-25T01:33:52ZengDove Medical PressOncoTargets and Therapy1178-69302019-11-01Volume 129551955749677Radiologic Complete Response In Lung Adenocarcinoma With Symptomatic Brain Metastasis After Systematic Therapy: A Case StudyChen JWang JZheng QWeng MWu XJianxin Chen,1 Junhui Wang,2 Qinhong Zheng,1 Meiling Weng,1 Xilin Wu1 1Department of Medical Oncology, Quzhou People’s Hospital, Quzhou, Zhejiang 324000, People’s Republic of China; 2Department of Radiation Oncology, Quzhou People’s Hospital, Quzhou, Zhejiang 324000, People’s Republic of ChinaCorrespondence: Xilin WuDepartment of Medical Oncology, Quzhou People’s Hospital, Quzhou, Zhejiang 324000, People’s Republic of ChinaEmail wuxilin1544@163.comAbstract: Patients diagnosed as lung adenocarcinoma with brain metastasis usually result in poor prognosis with limited survival time. Palliative systematic therapy has emerged as the primary choice for non-small cell lung cancer patients with brain metastasis harboring wild-type drive genes. However, the objective response rate and long-term survival for patients treated with this therapy remained unsatisfied. Herein, we present a case with lung adenocarcinoma accompanied with symptomatic brain metastasis who achieved radiologic complete response after receiving combined therapy including stereotactic body radiation therapy, anti-angiogenesis, and chemotherapy. He has achieved a duration of disease-free survival of thirty-six months, and is still in extension.Keywords: complete response, lung adenocarcinoma, brain metastasis, systematic therapyhttps://www.dovepress.com/radiologic-complete-response-in-lung-adenocarcinoma-with-symptomatic-b-peer-reviewed-article-OTTcomplete responselung adenocarcinomabrain metastasissystematic therapy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chen J Wang J Zheng Q Weng M Wu X |
spellingShingle |
Chen J Wang J Zheng Q Weng M Wu X Radiologic Complete Response In Lung Adenocarcinoma With Symptomatic Brain Metastasis After Systematic Therapy: A Case Study OncoTargets and Therapy complete response lung adenocarcinoma brain metastasis systematic therapy |
author_facet |
Chen J Wang J Zheng Q Weng M Wu X |
author_sort |
Chen J |
title |
Radiologic Complete Response In Lung Adenocarcinoma With Symptomatic Brain Metastasis After Systematic Therapy: A Case Study |
title_short |
Radiologic Complete Response In Lung Adenocarcinoma With Symptomatic Brain Metastasis After Systematic Therapy: A Case Study |
title_full |
Radiologic Complete Response In Lung Adenocarcinoma With Symptomatic Brain Metastasis After Systematic Therapy: A Case Study |
title_fullStr |
Radiologic Complete Response In Lung Adenocarcinoma With Symptomatic Brain Metastasis After Systematic Therapy: A Case Study |
title_full_unstemmed |
Radiologic Complete Response In Lung Adenocarcinoma With Symptomatic Brain Metastasis After Systematic Therapy: A Case Study |
title_sort |
radiologic complete response in lung adenocarcinoma with symptomatic brain metastasis after systematic therapy: a case study |
publisher |
Dove Medical Press |
series |
OncoTargets and Therapy |
issn |
1178-6930 |
publishDate |
2019-11-01 |
description |
Jianxin Chen,1 Junhui Wang,2 Qinhong Zheng,1 Meiling Weng,1 Xilin Wu1 1Department of Medical Oncology, Quzhou People’s Hospital, Quzhou, Zhejiang 324000, People’s Republic of China; 2Department of Radiation Oncology, Quzhou People’s Hospital, Quzhou, Zhejiang 324000, People’s Republic of ChinaCorrespondence: Xilin WuDepartment of Medical Oncology, Quzhou People’s Hospital, Quzhou, Zhejiang 324000, People’s Republic of ChinaEmail wuxilin1544@163.comAbstract: Patients diagnosed as lung adenocarcinoma with brain metastasis usually result in poor prognosis with limited survival time. Palliative systematic therapy has emerged as the primary choice for non-small cell lung cancer patients with brain metastasis harboring wild-type drive genes. However, the objective response rate and long-term survival for patients treated with this therapy remained unsatisfied. Herein, we present a case with lung adenocarcinoma accompanied with symptomatic brain metastasis who achieved radiologic complete response after receiving combined therapy including stereotactic body radiation therapy, anti-angiogenesis, and chemotherapy. He has achieved a duration of disease-free survival of thirty-six months, and is still in extension.Keywords: complete response, lung adenocarcinoma, brain metastasis, systematic therapy |
topic |
complete response lung adenocarcinoma brain metastasis systematic therapy |
url |
https://www.dovepress.com/radiologic-complete-response-in-lung-adenocarcinoma-with-symptomatic-b-peer-reviewed-article-OTT |
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