PGE stimulates COX-2 expression via EP2/4 receptors and acts in synergy with IL-1β in human follicular dendritic cell-like cells
PGE 2 is the major lipid mediator of inflammation produced by multiple cell types including follicular dendritic cells (FDCs) of the lymphoid tissue. We have investigated the immunoregulatory function of PGE 2 and its production mechanism using FDC-like cells isolated from human tonsil. Our recent o...
Main Authors: | Jihoon Nam, Bongjae Kwon, Yongdae Yoon, Jongseon Choe |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2018-08-01
|
Series: | European Journal of Inflammation |
Online Access: | https://doi.org/10.1177/2058739218796386 |
Similar Items
-
Prostaglandin E2 stimulates COX-2 expression via mitogen-activated protein kinase p38 but not ERK in human follicular dendritic cell-like cells
by: Whajung Cho, et al.
Published: (2020-04-01) -
Targeting COX-2/PGE(2) pathway in HIPK2 knockdown cancer cells: impact on dendritic cell maturation.
by: Alessia Garufi, et al.
Published: (2012-01-01) -
Infection of Dendritic Cells With Mycobacterium avium subspecies hominissuis Exhibits a Functionally Tolerogenic Phenotype in Response to Toll-Like Receptor Agonists via IL-10/Cox2/PGE2/EP2 Axis
by: Woo Sik Kim, et al.
Published: (2019-08-01) -
COXIBs and 2,5-dimethylcelecoxib counteract the hyperactivated Wnt/β-catenin pathway and COX-2/PGE2/EP4 signaling in glioblastoma cells
by: Aleksandra Majchrzak-Celińska, et al.
Published: (2021-05-01) -
Regulated expression of PTPRJ by COX-2/PGE2 axis in endothelial cells.
by: Xiaobing Xu, et al.
Published: (2014-01-01)