Sonographic assessment of some abdominal organs in children with sickle cell disease in Ilorin, Nigeria
Background: The irregular sickle cells can block blood vessels, causing tissue and organ damage and in most cases presented with pain as a result of organ ischemia. Ultrasonography is an easily available instrument for investigating abdominal organs which are most commonly affected by sickle cell di...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2021-01-01
|
Series: | Journal of Medical Ultrasound |
Subjects: | |
Online Access: | http://www.jmuonline.org/article.asp?issn=0929-6441;year=2021;volume=29;issue=2;spage=94;epage=98;aulast=Muftaudeen |
id |
doaj-138329ffba444ca7ac12dafdb4fd1033 |
---|---|
record_format |
Article |
spelling |
doaj-138329ffba444ca7ac12dafdb4fd10332021-07-07T13:33:56ZengWolters Kluwer Medknow PublicationsJournal of Medical Ultrasound0929-64412212-15522021-01-01292949810.4103/JMU.JMU_47_20Sonographic assessment of some abdominal organs in children with sickle cell disease in Ilorin, NigeriaBasirat MuftaudeenJoseph C EzeMuhammad SidiMutiat Nike MiftaudeenBackground: The irregular sickle cells can block blood vessels, causing tissue and organ damage and in most cases presented with pain as a result of organ ischemia. Ultrasonography is an easily available instrument for investigating abdominal organs which are most commonly affected by sickle cell disease (SCD). This study was aimed to assessing liver, gall bladder, spleen, and kidney in children with SCD in Ilorin, Kwara State. Methods: A prospective cross-sectional study was conducted among children with SCD in Ilorin from September 2017 to April 2018. An ethical approval was obtained from the Human Research and Ethics Committee of the Kwara State Ministry of Health. In this study, 106 children with SCD and 106 normal children for control were included. Abdominal ultrasound scan was performed on all the selected subjects and the findings were recorded on the data capture sheet. Descriptive and inferential statistic was used in the data analysis, SPSS version 20 was used and the P = 0.05. Results: In the children with SCD, hepatomegaly was found in 45 (42.5%), 29 (27.4%) had coarse echo pattern of liver and 16 (15.1%) had hyperechoic liver, 5 (4.7%) had gallbladder stone, 2 (1.9%) had gallbladder sludge, and 6 (5.6%) had thickened gallbladder wall. Twenty-five (23.6%) had splenomegaly, and 7 (6.6%) had autosplenectomy. Four (3.8%) showed reduced corticomedullary differentiation in each kidney, five (4.7%) in each kidney had mild calyceal dilatation. One (0.9%) had mild calyceal dilatation with reduced corticomedullary differentiation with accompanying loss of renal sinus fat. Conclusion: Abdominal ultrasound imaging for patients with SCD showed a high incidence of abdominal abnormalities, especially in solid organs such as liver, kidney, and spleen.http://www.jmuonline.org/article.asp?issn=0929-6441;year=2021;volume=29;issue=2;spage=94;epage=98;aulast=Muftaudeensickle cellultrasonographyilorin |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Basirat Muftaudeen Joseph C Eze Muhammad Sidi Mutiat Nike Miftaudeen |
spellingShingle |
Basirat Muftaudeen Joseph C Eze Muhammad Sidi Mutiat Nike Miftaudeen Sonographic assessment of some abdominal organs in children with sickle cell disease in Ilorin, Nigeria Journal of Medical Ultrasound sickle cell ultrasonography ilorin |
author_facet |
Basirat Muftaudeen Joseph C Eze Muhammad Sidi Mutiat Nike Miftaudeen |
author_sort |
Basirat Muftaudeen |
title |
Sonographic assessment of some abdominal organs in children with sickle cell disease in Ilorin, Nigeria |
title_short |
Sonographic assessment of some abdominal organs in children with sickle cell disease in Ilorin, Nigeria |
title_full |
Sonographic assessment of some abdominal organs in children with sickle cell disease in Ilorin, Nigeria |
title_fullStr |
Sonographic assessment of some abdominal organs in children with sickle cell disease in Ilorin, Nigeria |
title_full_unstemmed |
Sonographic assessment of some abdominal organs in children with sickle cell disease in Ilorin, Nigeria |
title_sort |
sonographic assessment of some abdominal organs in children with sickle cell disease in ilorin, nigeria |
publisher |
Wolters Kluwer Medknow Publications |
series |
Journal of Medical Ultrasound |
issn |
0929-6441 2212-1552 |
publishDate |
2021-01-01 |
description |
Background: The irregular sickle cells can block blood vessels, causing tissue and organ damage and in most cases presented with pain as a result of organ ischemia. Ultrasonography is an easily available instrument for investigating abdominal organs which are most commonly affected by sickle cell disease (SCD). This study was aimed to assessing liver, gall bladder, spleen, and kidney in children with SCD in Ilorin, Kwara State. Methods: A prospective cross-sectional study was conducted among children with SCD in Ilorin from September 2017 to April 2018. An ethical approval was obtained from the Human Research and Ethics Committee of the Kwara State Ministry of Health. In this study, 106 children with SCD and 106 normal children for control were included. Abdominal ultrasound scan was performed on all the selected subjects and the findings were recorded on the data capture sheet. Descriptive and inferential statistic was used in the data analysis, SPSS version 20 was used and the P = 0.05. Results: In the children with SCD, hepatomegaly was found in 45 (42.5%), 29 (27.4%) had coarse echo pattern of liver and 16 (15.1%) had hyperechoic liver, 5 (4.7%) had gallbladder stone, 2 (1.9%) had gallbladder sludge, and 6 (5.6%) had thickened gallbladder wall. Twenty-five (23.6%) had splenomegaly, and 7 (6.6%) had autosplenectomy. Four (3.8%) showed reduced corticomedullary differentiation in each kidney, five (4.7%) in each kidney had mild calyceal dilatation. One (0.9%) had mild calyceal dilatation with reduced corticomedullary differentiation with accompanying loss of renal sinus fat. Conclusion: Abdominal ultrasound imaging for patients with SCD showed a high incidence of abdominal abnormalities, especially in solid organs such as liver, kidney, and spleen. |
topic |
sickle cell ultrasonography ilorin |
url |
http://www.jmuonline.org/article.asp?issn=0929-6441;year=2021;volume=29;issue=2;spage=94;epage=98;aulast=Muftaudeen |
work_keys_str_mv |
AT basiratmuftaudeen sonographicassessmentofsomeabdominalorgansinchildrenwithsicklecelldiseaseinilorinnigeria AT josephceze sonographicassessmentofsomeabdominalorgansinchildrenwithsicklecelldiseaseinilorinnigeria AT muhammadsidi sonographicassessmentofsomeabdominalorgansinchildrenwithsicklecelldiseaseinilorinnigeria AT mutiatnikemiftaudeen sonographicassessmentofsomeabdominalorgansinchildrenwithsicklecelldiseaseinilorinnigeria |
_version_ |
1721315447948705792 |