Temporal expression of bacterial proteins instructs host CD4 T cell expansion and Th17 development.
Pathogens can substantially alter gene expression within an infected host depending on metabolic or virulence requirements in different tissues, however, the effect of these alterations on host immunity are unclear. Here we visualized multiple CD4 T cell responses to temporally expressed proteins in...
Main Authors: | Seung-Joo Lee, James B McLachlan, Jonathan R Kurtz, Danhua Fan, Sebastian E Winter, Andreas J Baumler, Marc K Jenkins, Stephen J McSorley |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC3262010?pdf=render |
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