Effect of Nɛ-carboxymethyllysine on oxidative stress and the glutathione system in beta cells
One of the pathways involved in the pathogenesis of diabetic complications is the formation of excessive levels of advanced glycation end (AGE) products. Nɛ-carboxymethyllysine (CML) is one of the best-characterized AGEs. Because little is known about the effects of AGEs on pancreatic beta cells, we...
Main Authors: | Daniëlle M.P.H.J. Boesten, Atlanta G.I.M. Elie, Marie-José Drittij-Reijnders, Gertjan J.M. den Hartog, Aalt Bast |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-01-01
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Series: | Toxicology Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214750014000377 |
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