Effect of Nɛ-carboxymethyllysine on oxidative stress and the glutathione system in beta cells

Effect of Nɛ-carboxymethyllysine on oxidative stress and the glutathione system in beta cells

One of the pathways involved in the pathogenesis of diabetic complications is the formation of excessive levels of advanced glycation end (AGE) products. Nɛ-carboxymethyllysine (CML) is one of the best-characterized AGEs. Because little is known about the effects of AGEs on pancreatic beta cells, we...

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Bibliographic Details
Main Authors:	Daniëlle M.P.H.J. Boesten, Atlanta G.I.M. Elie, Marie-José Drittij-Reijnders, Gertjan J.M. den Hartog, Aalt Bast
Format:	Article
Language:	English
Published:	Elsevier 2014-01-01
Series:	Toxicology Reports
Subjects:	Glutathione Beta cells N(epsilon)-carboxymethyllysine Advanced glycation end product Oxidative stress
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214750014000377

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