Single-Cell RNA-Sequencing Shift in the Interaction Pattern Between Glioma Stem Cells and Immune Cells During Tumorigenesis

Single-Cell RNA-Sequencing Shift in the Interaction Pattern Between Glioma Stem Cells and Immune Cells During Tumorigenesis

Glioblastoma is one of the most common neoplasms in the central nervous system characterized by limited immune response and unlimited expansion capability. Cancer stem cells (GSCs), a small fraction of the tumor cells, possess a pivotal regulation capability in the tumor microenvironment with a supe...

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Bibliographic Details
Main Authors: You Zhai, Guanzhang Li, Renpeng Li, Yuanhao Chang, Yuemei Feng, Di Wang, Fan Wu, Wei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
glioma stem cell
T cell
single cell sequence
immunosuppression
tumorigenesis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.581209/full

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