Genetic characteristics of the human hepatic stellate cell line LX-2.

The human hepatic cell line LX-2 has been described as tool to study mechanisms of hepatic fibrogenesis and the testing of antifibrotic compounds. It was originally generated by immortalisation with the Simian Vacuolating Virus 40 (SV40) transforming (T) antigen and subsequent propagation in low ser...

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Bibliographic Details
Main Authors: Ralf Weiskirchen, Jörg Weimer, Steffen K Meurer, Anja Kron, Barbara Seipel, Inga Vater, Norbert Arnold, Reiner Siebert, Lieming Xu, Scott L Friedman, Carsten Bergmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3792989?pdf=render