A comparison of single molecule and amplification based sequencing of cancer transcriptomes.

A comparison of single molecule and amplification based sequencing of cancer transcriptomes.

The second wave of next generation sequencing technologies, referred to as single-molecule sequencing (SMS), carries the promise of profiling samples directly without employing polymerase chain reaction steps used by amplification-based sequencing (AS) methods. To examine the merits of both technolo...

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Bibliographic Details
Main Authors: Lee T Sam, Doron Lipson, Tal Raz, Xuhong Cao, John Thompson, Patrice M Milos, Dan Robinson, Arul M Chinnaiyan, Chandan Kumar-Sinha, Christopher A Maher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3046973?pdf=render

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