Challenges in optimizing chemoradiation in locally advanced non small-cell lung cancers in India
Data supporting use of concurrent chemoradiation in locally advanced lung cancers comes from clinical trials from developed countries. Applicability and outcomes of such schedules in developing countries is not widely reported. There are various challenges in delivering chemoradiation in locally adv...
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2013-01-01
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doaj-13ff84221b764ccfab7178f9c5a0b2212020-12-02T17:19:54ZengThieme Medical and Scientific Publishers Pvt. Ltd.South Asian Journal of Cancer2278-330X2278-43062013-01-012426527110.4103/2278-330X.119893Challenges in optimizing chemoradiation in locally advanced non small-cell lung cancers in IndiaSushma AgrawalData supporting use of concurrent chemoradiation in locally advanced lung cancers comes from clinical trials from developed countries. Applicability and outcomes of such schedules in developing countries is not widely reported. There are various challenges in delivering chemoradiation in locally advanced non small cell lung cancer in developing countries which is highlighted by an audit of patients treated with chemoradiation in our center. This article deals with the challenges in the context of a developing country. We conclude that sequential chemoradiotherapy is better tolerated than concurrent chemoradiation in Indian patients with locally advanced non-small cell lung cancers. Patients with stage IIIa, normal weight or overweight, and adequate baseline pulmonary function should be offered concurrent chemoradiation.http://journal.sajc.org/article.asp?issn=2278-330X;year=2013;volume=2;issue=4;spage=265;epage=271;aulast=AgrawalLocally advanced non-small cell Lung cancerconcurrent chemoradiationdeveloping countriesnon-small-cell lung cancerchemoradiation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sushma Agrawal |
spellingShingle |
Sushma Agrawal Challenges in optimizing chemoradiation in locally advanced non small-cell lung cancers in India South Asian Journal of Cancer Locally advanced non-small cell Lung cancer concurrent chemoradiation developing countries non-small-cell lung cancer chemoradiation |
author_facet |
Sushma Agrawal |
author_sort |
Sushma Agrawal |
title |
Challenges in optimizing chemoradiation in locally advanced non small-cell lung cancers in India |
title_short |
Challenges in optimizing chemoradiation in locally advanced non small-cell lung cancers in India |
title_full |
Challenges in optimizing chemoradiation in locally advanced non small-cell lung cancers in India |
title_fullStr |
Challenges in optimizing chemoradiation in locally advanced non small-cell lung cancers in India |
title_full_unstemmed |
Challenges in optimizing chemoradiation in locally advanced non small-cell lung cancers in India |
title_sort |
challenges in optimizing chemoradiation in locally advanced non small-cell lung cancers in india |
publisher |
Thieme Medical and Scientific Publishers Pvt. Ltd. |
series |
South Asian Journal of Cancer |
issn |
2278-330X 2278-4306 |
publishDate |
2013-01-01 |
description |
Data supporting use of concurrent chemoradiation in locally advanced lung cancers comes from clinical trials from developed countries. Applicability and outcomes of such schedules in developing countries is not widely reported. There are various challenges in delivering chemoradiation in locally advanced non small cell lung cancer in developing countries which is highlighted by an audit of patients treated with chemoradiation in our center. This article deals with the challenges in the context of a developing country. We conclude that sequential chemoradiotherapy is better tolerated than concurrent chemoradiation in Indian patients with locally advanced non-small cell lung cancers. Patients with stage IIIa, normal weight or overweight, and adequate baseline pulmonary function should be offered concurrent chemoradiation. |
topic |
Locally advanced non-small cell Lung cancer concurrent chemoradiation developing countries non-small-cell lung cancer chemoradiation |
url |
http://journal.sajc.org/article.asp?issn=2278-330X;year=2013;volume=2;issue=4;spage=265;epage=271;aulast=Agrawal |
work_keys_str_mv |
AT sushmaagrawal challengesinoptimizingchemoradiationinlocallyadvancednonsmallcelllungcancersinindia |
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1724404824894603264 |