Identification and functional characterization of cardiac pacemaker cells in zebrafish.
In the mammalian heart a conduction system of nodes and conducting cells generates and transduces the electrical signals evoking myocardial contractions. Specialized pacemaker cells initiating and controlling cardiac contraction rhythmicity are localized in an anatomically identifiable structure of...
Main Authors: | Federico Tessadori, Jan Hendrik van Weerd, Silja B Burkhard, Arie O Verkerk, Emma de Pater, Bastiaan J Boukens, Aryan Vink, Vincent M Christoffels, Jeroen Bakkers |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3473062?pdf=render |
Similar Items
-
On the Evolution of the Cardiac Pacemaker
by: Silja Burkhard, et al.
Published: (2017-04-01) -
Twisting of the zebrafish heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process
by: Federico Tessadori, et al.
Published: (2021-08-01) -
Spatially resolved RNA-sequencing of the embryonic heart identifies a role for Wnt/β-catenin signaling in autonomic control of heart rate
by: Silja Barbara Burkhard, et al.
Published: (2018-02-01) -
Trait-associated noncoding variant regions affect TBX3 regulation and cardiac conduction
by: Jan Hendrik van Weerd, et al.
Published: (2020-07-01) -
Identification and Characterization of a Transcribed Distal Enhancer Involved in Cardiac Kcnh2 Regulation
by: Malou van den Boogaard, et al.
Published: (2019-09-01)