Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis

Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis

Christopher A GirkinUniversity of Alabama at Birmingham School of Medicine, Birmingham, AL, USAAbstract: Glaucoma disproportionately affects individual of African ancestry. Additionally, racial differences in the optic nerve head have been well described that may alter the vulnerability to intraocul...

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Main Author: Christopher A Girkin
Format: Article
Language:English
Published: Dove Medical Press 2008-03-01
Series:Clinical Ophthalmology
Online Access:http://www.dovepress.com/differences-in-optic-nerve-structure-between-individuals-of-predominan-a361
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spelling doaj-141c5240d0c84fc097b4805d6fbbe6e12020-11-24T21:06:07ZengDove Medical PressClinical Ophthalmology1177-54671177-54832008-03-012008Issue 16569Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesisChristopher A GirkinChristopher A GirkinUniversity of Alabama at Birmingham School of Medicine, Birmingham, AL, USAAbstract: Glaucoma disproportionately affects individual of African ancestry. Additionally, racial differences in the optic nerve head have been well described that may alter the vulnerability to intraocular pressure related injury and, in addition, alter the clinical ability to detect the presence of early optic nerve injury. This paper will review the literature describing racial differences in the optic nerve head between individuals of African and European ancestry with regards to the potential effects of these differences on the ability to detect glaucoma in different racial groups and to potential differences in the pathogenesis of glaucomatous injury.Keywords: primary open angle glaucoma, African American, optic nerve, optic disc, retinal nerve fiber layer http://www.dovepress.com/differences-in-optic-nerve-structure-between-individuals-of-predominan-a361
collection DOAJ
language English
format Article
sources DOAJ
author Christopher A Girkin
spellingShingle Christopher A Girkin
Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis
Clinical Ophthalmology
author_facet Christopher A Girkin
author_sort Christopher A Girkin
title Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis
title_short Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis
title_full Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis
title_fullStr Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis
title_full_unstemmed Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis
title_sort differences in optic nerve structure between individuals of predominantly african and european ancestry: implications for disease detection and pathogenesis
publisher Dove Medical Press
series Clinical Ophthalmology
issn 1177-5467
1177-5483
publishDate 2008-03-01
description Christopher A GirkinUniversity of Alabama at Birmingham School of Medicine, Birmingham, AL, USAAbstract: Glaucoma disproportionately affects individual of African ancestry. Additionally, racial differences in the optic nerve head have been well described that may alter the vulnerability to intraocular pressure related injury and, in addition, alter the clinical ability to detect the presence of early optic nerve injury. This paper will review the literature describing racial differences in the optic nerve head between individuals of African and European ancestry with regards to the potential effects of these differences on the ability to detect glaucoma in different racial groups and to potential differences in the pathogenesis of glaucomatous injury.Keywords: primary open angle glaucoma, African American, optic nerve, optic disc, retinal nerve fiber layer
url http://www.dovepress.com/differences-in-optic-nerve-structure-between-individuals-of-predominan-a361
work_keys_str_mv AT christopheragirkin differencesinopticnervestructurebetweenindividualsofpredominantlyafricanandeuropeanancestryimplicationsfordiseasedetectionandpathogenesis
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