Immunohistochemical Localisation of PDE5 in Rat Lung during Pre- and Postnatal Development

In mammalian lung, at the transition to extrauterine life, NO/cGMP signal transduction system is known to play crucial roles in the regulation of vascular resistance and is supposed to act in angiogenesis. PDE5, which is the most abundant cGMP metabolizing enzyme within the lung, is highly expressed...

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Bibliographic Details
Main Authors: Angela Scipioni, Mauro Giorgi, Valeria Nuccetelli, Stefania Stefanini
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2009/932961

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