Adaptation of Candida albicans to environmental pH induces cell wall remodelling and enhances innate immune recognition.
Candida albicans is able to proliferate in environments that vary dramatically in ambient pH, a trait required for colonising niches such as the stomach, vaginal mucosal and the GI tract. Here we show that growth in acidic environments involves cell wall remodelling which results in enhanced chitin...
Main Authors: | Sarah L Sherrington, Eleanor Sorsby, Nabeel Mahtey, Pizga Kumwenda, Megan D Lenardon, Ian Brown, Elizabeth R Ballou, Donna M MacCallum, Rebecca A Hall |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-05-01
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Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1006403 |
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