Consistency of Fractional Anisotropy Values Using Different Combinations of b-Value and Time of Echo (TE) in Diffusion Tensor Imaging of Normal Brain White Matter
Introduction: Fractional Anisotropy (FA) values are considered as a solid concrete index for determining white matter integrity in ageing and neurodegenerative diseases. FA is more comparable and reliable parameter than individual diffusivity parameters. A b-value and Time of Echo (TE) significa...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
JCDR Research and Publications Private Limited
2018-12-01
|
Series: | Journal of Clinical and Diagnostic Research |
Subjects: | |
Online Access: | https://jcdr.net/articles/PDF/12315/38089_CE[Ra1]_F(SL)_PF1(AGAK)_PFA(AK)_PN(P).pdf |
id |
doaj-1461dd7027224c939b4fc712dd15859f |
---|---|
record_format |
Article |
spelling |
doaj-1461dd7027224c939b4fc712dd15859f2020-11-25T02:10:32ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2018-12-011212TC01TC0410.7860/JCDR/2018/38089.12315Consistency of Fractional Anisotropy Values Using Different Combinations of b-Value and Time of Echo (TE) in Diffusion Tensor Imaging of Normal Brain White MatterRahul P Kotian0K Prakashini1Sreekumaran Nair2M Satish Babu3Selection Grade Assistant Professor, Department of Medical Imaging Technology, Manipal School of Allied Health Sciences, MAHE, Manipal, Karnataka, India.Professor, Department of Radiodiagnosis and Imaging, Kasturba Medical College, MAHE, Manipal, Karnataka, India.Professor, Department of Medical Biometrics and Informatics (Biostatistics), JIPMER, Puducherry, Tamil Nadu, India.Consultant Radiologist, Manipal Hospitals, Vijayawada, Andhra Pradesh, India.Introduction: Fractional Anisotropy (FA) values are considered as a solid concrete index for determining white matter integrity in ageing and neurodegenerative diseases. FA is more comparable and reliable parameter than individual diffusivity parameters. A b-value and Time of Echo (TE) significantly affect the reproducibility and accuracy of Diffusion Tensor Imaging (DTI) derived indices at 1.5 Tesla (T) MRI machines in grey and white matter. Hence, no fixed b-value and TE protocol combination is recommended in literature to obtain consistent FA values, as it is a relatively new imaging technique. Aim: To check the consistency of FA values using different combinations of b-value and TE in DTI of normal brain white matter and to establish a standardised protocol for calculating FA values in different regions of normal brain white matter of the corpus callosum, centrum semiovale and pons. Materials and Methods: A cross-sectional study of 23 healthy participants without neurological abnormalities using 1.5 T MRI, DTI of brain white matter was performed. FA values were measured at the corpus callosum, centrum semiovale and pons using fiber track analysis in six different combinations of b-value and TE. Results: The FA values with least coefficient of variation was found with a b-value of 1000 s/mm2 and TE 100 ms. Conclusion: The current study established a standardised protocol for calculating FA values in different regions of normal brain white matter of the corpus callosum, centrum semiovale and pons.https://jcdr.net/articles/PDF/12315/38089_CE[Ra1]_F(SL)_PF1(AGAK)_PFA(AK)_PN(P).pdfcentrum semiovalecorpus callosumpons |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Rahul P Kotian K Prakashini Sreekumaran Nair M Satish Babu |
spellingShingle |
Rahul P Kotian K Prakashini Sreekumaran Nair M Satish Babu Consistency of Fractional Anisotropy Values Using Different Combinations of b-Value and Time of Echo (TE) in Diffusion Tensor Imaging of Normal Brain White Matter Journal of Clinical and Diagnostic Research centrum semiovale corpus callosum pons |
author_facet |
Rahul P Kotian K Prakashini Sreekumaran Nair M Satish Babu |
author_sort |
Rahul P Kotian |
title |
Consistency of Fractional Anisotropy Values Using Different Combinations of b-Value and Time of Echo (TE) in Diffusion Tensor Imaging of Normal Brain White Matter |
title_short |
Consistency of Fractional Anisotropy Values Using Different Combinations of b-Value and Time of Echo (TE) in Diffusion Tensor Imaging of Normal Brain White Matter |
title_full |
Consistency of Fractional Anisotropy Values Using Different Combinations of b-Value and Time of Echo (TE) in Diffusion Tensor Imaging of Normal Brain White Matter |
title_fullStr |
Consistency of Fractional Anisotropy Values Using Different Combinations of b-Value and Time of Echo (TE) in Diffusion Tensor Imaging of Normal Brain White Matter |
title_full_unstemmed |
Consistency of Fractional Anisotropy Values Using Different Combinations of b-Value and Time of Echo (TE) in Diffusion Tensor Imaging of Normal Brain White Matter |
title_sort |
consistency of fractional anisotropy values using different combinations of b-value and time of echo (te) in diffusion tensor imaging of normal brain white matter |
publisher |
JCDR Research and Publications Private Limited |
series |
Journal of Clinical and Diagnostic Research |
issn |
2249-782X 0973-709X |
publishDate |
2018-12-01 |
description |
Introduction: Fractional Anisotropy (FA) values are considered
as a solid concrete index for determining white matter integrity in
ageing and neurodegenerative diseases. FA is more comparable
and reliable parameter than individual diffusivity parameters.
A b-value and Time of Echo (TE) significantly affect the
reproducibility and accuracy of Diffusion Tensor Imaging (DTI)
derived indices at 1.5 Tesla (T) MRI machines in grey and white
matter. Hence, no fixed b-value and TE protocol combination is
recommended in literature to obtain consistent FA values, as it
is a relatively new imaging technique.
Aim: To check the consistency of FA values using different
combinations of b-value and TE in DTI of normal brain white
matter and to establish a standardised protocol for calculating
FA values in different regions of normal brain white matter of the
corpus callosum, centrum semiovale and pons.
Materials and Methods: A cross-sectional study of 23 healthy
participants without neurological abnormalities using 1.5 T
MRI, DTI of brain white matter was performed. FA values were
measured at the corpus callosum, centrum semiovale and pons
using fiber track analysis in six different combinations of b-value
and TE.
Results: The FA values with least coefficient of variation was
found with a b-value of 1000 s/mm2
and TE 100 ms.
Conclusion: The current study established a standardised
protocol for calculating FA values in different regions of normal
brain white matter of the corpus callosum, centrum semiovale
and pons. |
topic |
centrum semiovale corpus callosum pons |
url |
https://jcdr.net/articles/PDF/12315/38089_CE[Ra1]_F(SL)_PF1(AGAK)_PFA(AK)_PN(P).pdf |
work_keys_str_mv |
AT rahulpkotian consistencyoffractionalanisotropyvaluesusingdifferentcombinationsofbvalueandtimeofechoteindiffusiontensorimagingofnormalbrainwhitematter AT kprakashini consistencyoffractionalanisotropyvaluesusingdifferentcombinationsofbvalueandtimeofechoteindiffusiontensorimagingofnormalbrainwhitematter AT sreekumarannair consistencyoffractionalanisotropyvaluesusingdifferentcombinationsofbvalueandtimeofechoteindiffusiontensorimagingofnormalbrainwhitematter AT msatishbabu consistencyoffractionalanisotropyvaluesusingdifferentcombinationsofbvalueandtimeofechoteindiffusiontensorimagingofnormalbrainwhitematter |
_version_ |
1724919147511414784 |