Significance of color doppler ultrasonography in the assessment of pancreatic carcinoma vascular invasion

• Main Authors: Alempijević Tamara, Kovačević Nada, Tomić Dragan, Đuranović Srđan, Krstić Miodrag
• Format: Article
• Language: English
• Published: Military Health Department, Ministry of Defance, Serbia 2006-01-01
• Series: Vojnosanitetski Pregled
• Subjects: pancreatic neoplasm; ultrasonography, doppler, color; neoplasm invasiveness; blood vessels; prognosis; palliative care
• Online Access: http://www.doiserbia.nb.rs/img/doi/0042-8450/2006/0042-84500610857A.pdf

Background/Aim. It is highly appreciated to provide exact data on vascular invasion of pancreatic carcinoma relying as much as possible on non-invasive diagnostic procedures. Color Doppler ultrasonography has been proven as an efficient method for clinical staging of pancreatic carcinoma essential for therapeutic decisions. The aim of this study was to provide an analysis of the sensitivity and specificity for color Doppler ultrasonography in patients suffering from pancreatic carcinoma. Methods. We performed color Doppler ultrasonography examination in 43 patients with pancreatic carcinoma prior to the surgery. The findings of ultrasonography on neoplasm vascular invasion were correlated to the findings obtained during the subsequent surgical procedures. An estimation of neoplastic invasion of certain blood vessels including portal vein, celiac trunk, and superior mesenteric artery and vein is critical for decision making regarding surgical treatment. The patients with metastases of pancreatic carcinoma were excluded from the study. Results. Comparing color Doppler and the surgical findings we estimated the sensitivity for detection of neoplastic vascular invasion ranging from 79−93%, whereas the specificity range was from 83−93%. Conclusion. Color Doppler ultrasonography is a sufficiently sensitive and specific method for evaluation of vascular invasion in pancreatic carcinoma patients. Since color Doppler ultrasonography is a non-invasive, radiation free, and inexpensive diagnostic tool, considering also the results of this and similar studies we could strongly recommend its use for an initial presurgical evaluation of vascular invasion in pancreatic carcinoma patients.