Thirst sensation and oral dryness following alcohol intake
Substantial acute and chronic intakes of alcohol or ethanol (EtOH) severely influence oral sensations, such as thirst and oral dryness (dry mouth, xerostomia). Thirst sensation and oral dryness are primarily caused by the activation of neurons in brain regions, including the circumventricular organs...
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2017-08-01
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doaj-1494b482841a4516901a58ce5deacbc12020-11-24T22:59:20ZengElsevierJapanese Dental Science Review1882-76162017-08-01533788510.1016/j.jdsr.2016.12.001Thirst sensation and oral dryness following alcohol intakeKiyotoshi InenagaKentaro OnoSuzuro HitomiAyu KurokiIzumi UjiharaSubstantial acute and chronic intakes of alcohol or ethanol (EtOH) severely influence oral sensations, such as thirst and oral dryness (dry mouth, xerostomia). Thirst sensation and oral dryness are primarily caused by the activation of neurons in brain regions, including the circumventricular organs and hypothalamus, which are referred to as the dipsogenic center, and by a decrease in salivary secretion, respectively. The sensation of thirst experienced after heavy-alcohol drinking is widely regarded as a consequence of EtOH-induced diuresis; however, EtOH in high doses induces anti-diuresis. Recently, it has been proposed that the ethanol metabolite acetaldehyde induces thirst via two distinct processes in the central nervous system from EtOH-induced diuresis, based on the results of animal experiments. The present review describes new insights regarding the induction mechanism of thirst sensation and oral dryness after drinking alcohol.http://www.sciencedirect.com/science/article/pii/S1882761616300631EthanolThirstOral drynessAcetaldehydeAngiotensin |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kiyotoshi Inenaga Kentaro Ono Suzuro Hitomi Ayu Kuroki Izumi Ujihara |
spellingShingle |
Kiyotoshi Inenaga Kentaro Ono Suzuro Hitomi Ayu Kuroki Izumi Ujihara Thirst sensation and oral dryness following alcohol intake Japanese Dental Science Review Ethanol Thirst Oral dryness Acetaldehyde Angiotensin |
author_facet |
Kiyotoshi Inenaga Kentaro Ono Suzuro Hitomi Ayu Kuroki Izumi Ujihara |
author_sort |
Kiyotoshi Inenaga |
title |
Thirst sensation and oral dryness following alcohol intake |
title_short |
Thirst sensation and oral dryness following alcohol intake |
title_full |
Thirst sensation and oral dryness following alcohol intake |
title_fullStr |
Thirst sensation and oral dryness following alcohol intake |
title_full_unstemmed |
Thirst sensation and oral dryness following alcohol intake |
title_sort |
thirst sensation and oral dryness following alcohol intake |
publisher |
Elsevier |
series |
Japanese Dental Science Review |
issn |
1882-7616 |
publishDate |
2017-08-01 |
description |
Substantial acute and chronic intakes of alcohol or ethanol (EtOH) severely influence oral sensations, such as thirst and oral dryness (dry mouth, xerostomia). Thirst sensation and oral dryness are primarily caused by the activation of neurons in brain regions, including the circumventricular organs and hypothalamus, which are referred to as the dipsogenic center, and by a decrease in salivary secretion, respectively. The sensation of thirst experienced after heavy-alcohol drinking is widely regarded as a consequence of EtOH-induced diuresis; however, EtOH in high doses induces anti-diuresis. Recently, it has been proposed that the ethanol metabolite acetaldehyde induces thirst via two distinct processes in the central nervous system from EtOH-induced diuresis, based on the results of animal experiments. The present review describes new insights regarding the induction mechanism of thirst sensation and oral dryness after drinking alcohol. |
topic |
Ethanol Thirst Oral dryness Acetaldehyde Angiotensin |
url |
http://www.sciencedirect.com/science/article/pii/S1882761616300631 |
work_keys_str_mv |
AT kiyotoshiinenaga thirstsensationandoraldrynessfollowingalcoholintake AT kentaroono thirstsensationandoraldrynessfollowingalcoholintake AT suzurohitomi thirstsensationandoraldrynessfollowingalcoholintake AT ayukuroki thirstsensationandoraldrynessfollowingalcoholintake AT izumiujihara thirstsensationandoraldrynessfollowingalcoholintake |
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