Correlation of Serum Interferon Gamma and Neopterin Concentrations in Africans with Various Diseases
Concentrations of interferon gamma in serum and of neopterin in serum and urine were determined in 55 Tanzanians attending a local hospital for various diseases or complaints. For comparison, serum concentrations of interferon gamma and of neopterin were also measured in 76 clinically healthy Austri...
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De Gruyter
1989-05-01
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Series: | Pteridines |
Online Access: | https://doi.org/10.1515/pteridines.1989.1.2.119 |
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doaj-149f6934e80a454fb2922589200826722021-09-05T13:59:57ZengDe GruyterPteridines0933-48072195-47201989-05-011211912410.1515/pteridines.1989.1.2.119Correlation of Serum Interferon Gamma and Neopterin Concentrations in Africans with Various DiseasesReibnegger Gilbert0Fuchs Dietmar1Hausen Arno2Schmutzhard Erich3Werner Ernst R.4Werner-Felmayer Gabriele5Dierich Manfred P.6Wachter Helmut7Institut für Medizinische Chemie und Biochemie, Universitat InnsbruckInstitut für Medizinische Chemie und Biochemie, Universitat InnsbruckInstitut für Medizinische Chemie und Biochemie, Universitat InnsbruckUniversitätsklinik für Neurologie, Universität lnnsbruckInstitut für Medizinische Chemie und Biochemie, Universitat InnsbruckInstitut für Medizinische Chemie und Biochemie, Universitat InnsbruckInstitut für Hygiene, Universitat InnsbruckInstitut für Medizinische Chemie und Biochemie, Universitat InnsbruckConcentrations of interferon gamma in serum and of neopterin in serum and urine were determined in 55 Tanzanians attending a local hospital for various diseases or complaints. For comparison, serum concentrations of interferon gamma and of neopterin were also measured in 76 clinically healthy Austrian blood donors. Both interferon gamma and neopterin concentrations were significantly higher in patients than in blood donors. Both analytes were significantly correlated with each other, and both exhibited similar behaviour in dependence on clinical diagnosis. The results support use of neopterin determination for indirect measurement of endogenous production of interferon gamma.https://doi.org/10.1515/pteridines.1989.1.2.119 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Reibnegger Gilbert Fuchs Dietmar Hausen Arno Schmutzhard Erich Werner Ernst R. Werner-Felmayer Gabriele Dierich Manfred P. Wachter Helmut |
spellingShingle |
Reibnegger Gilbert Fuchs Dietmar Hausen Arno Schmutzhard Erich Werner Ernst R. Werner-Felmayer Gabriele Dierich Manfred P. Wachter Helmut Correlation of Serum Interferon Gamma and Neopterin Concentrations in Africans with Various Diseases Pteridines |
author_facet |
Reibnegger Gilbert Fuchs Dietmar Hausen Arno Schmutzhard Erich Werner Ernst R. Werner-Felmayer Gabriele Dierich Manfred P. Wachter Helmut |
author_sort |
Reibnegger Gilbert |
title |
Correlation of Serum Interferon Gamma and Neopterin Concentrations in Africans with Various Diseases |
title_short |
Correlation of Serum Interferon Gamma and Neopterin Concentrations in Africans with Various Diseases |
title_full |
Correlation of Serum Interferon Gamma and Neopterin Concentrations in Africans with Various Diseases |
title_fullStr |
Correlation of Serum Interferon Gamma and Neopterin Concentrations in Africans with Various Diseases |
title_full_unstemmed |
Correlation of Serum Interferon Gamma and Neopterin Concentrations in Africans with Various Diseases |
title_sort |
correlation of serum interferon gamma and neopterin concentrations in africans with various diseases |
publisher |
De Gruyter |
series |
Pteridines |
issn |
0933-4807 2195-4720 |
publishDate |
1989-05-01 |
description |
Concentrations of interferon gamma in serum and of neopterin in serum and urine were determined in 55 Tanzanians attending a local hospital for various diseases or complaints. For comparison, serum concentrations of interferon gamma and of neopterin were also measured in 76 clinically healthy Austrian blood donors. Both interferon gamma and neopterin concentrations were significantly higher in patients than in blood donors. Both analytes were significantly correlated with each other, and both exhibited similar behaviour in dependence on clinical diagnosis. The results support use of neopterin determination for indirect measurement of endogenous production of interferon gamma. |
url |
https://doi.org/10.1515/pteridines.1989.1.2.119 |
work_keys_str_mv |
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