Triple oral beta-lactam containing therapy for Buruli ulcer treatment shortening.

The potential use of clinically approved beta-lactams for Buruli ulcer (BU) treatment was investigated with representative classes analyzed in vitro for activity against Mycobacterium ulcerans. Beta-lactams tested were effective alone and displayed a strong synergistic profile in combination with an...

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Bibliographic Details
Main Authors: María Pilar Arenaz-Callao, Rubén González Del Río, Ainhoa Lucía Quintana, Charles J Thompson, Alfonso Mendoza-Losana, Santiago Ramón-García
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6366712?pdf=render