Prevalence and factors associated with dyslipidemia after liver transplantation

• Main Authors: Hélem de Sena Ribeiro, Lucilene Rezende Anastácio, Lívia Garcia Ferreira, Érika Barbosa Lagares, Agnaldo Soares Lima, Maria Isabel Toulson Davisson Correia
• Format: Article
• Language: English
• Published: Associação Médica Brasileira 2014-07-01
• Series: Revista da Associação Médica Brasileira
• Subjects: dislipidemia; lipoproteínas; prevalência; transplante de fígado
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302014000400365&lng=en&tlng=en

Objective: to determine the prevalence of abnormal total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL) and triglycerides in patients undergoing liver transplantation (LTx) and to identify predictors of these disorders. Methods: cross-sectional study to assess the prevalence of dyslipidemia in patients undergoing LTx. Demographic, socioeconomic, clinical, anthropometric and dietetic data were collected to determine the association with dyslipidemia using univariate and multivariate statistical analysis. Results: 136 patients were evaluated, 68.1% of which had at least one type of dyslipidemia. The triglyceride level was high in 32.4% of cases, with low HDL in 49.3% of patients and high LDL levels in only 8.8%. High total cholesterol was observed in 16.2% of the study population and was associated with the recommendation for transplantation due to ethanolic cirrhosis (OR = 2.7) and a greater number of hours slept per night (OR = 1.5). Conclusion: many patients presented dyslipidemia after transplantation, demonstrating the need for interventions in relation to modifiable factors associated with dyslipidemias that can mitigate or prevent these disorders.