The role of the breast cancer susceptibility gene 1 (BRCA1) in sporadic epithelial ovarian cancer

<p>Abstract</p> <p>Mutations within the BRCA1 tumor suppressor gene occur frequently in familial epithelial ovarian carcinomas but they are a rare event in the much more prevalent sporadic form of the disease. However, decreased BRCA1 expression occurs frequently in sporadic tumors...

Full description

Bibliographic Details
Main Authors: Mueller Christopher R, McCoy Marcia L, Roskelley Calvin D
Format: Article
Language:English
Published: BMC 2003-10-01
Series:Reproductive Biology and Endocrinology
Online Access:http://www.RBEj.com/content/1/1/72