A human H1-HBB11-GFP reporter embryonic stem cell line (WAe001-A-2) generated using TALEN-based genome editing
Hemoglobin production during mammalian development is characterized by temporal switches of the genes coding for the α- and ß-globin chains. Defects in this controlled process can lead to hemoglobinapathies such as sickle cell disease and ß-thalassemia. The ability of human embryonic stem cells (hES...
Main Authors: | Vera Alexeeva, Iraz T. Aydin, Christoph Schaniel, Alec W. Stranahan, Sunita L. D'Souza, James J. Bieker |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2020-05-01
|
Series: | Stem Cell Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506120301380 |
Similar Items
-
A human MIXL1 green fluorescent protein reporter embryonic stem cell line engineered using TALEN-based genome editing
by: Vera Alexeeva, et al.
Published: (2016-07-01) -
TALEN-mediated biallelic inactivation of MYB in human embryonic stem cell lines WAe001-A-45 and WAe001-A-46
by: Chenyu Fan, et al.
Published: (2020-07-01) -
Generation of human embryonic stem cell lines (WAe001-A-67,WAe001-A-68) with TEAD1 and TEAD4 expression by the PiggyBac transposon system
by: Yingyi Quan, et al.
Published: (2021-07-01) -
Generation of a SMO homozygous knockout human embryonic stem cell line WAe001-A-16 by CRISPR/Cas9 editing
by: Feima Wu, et al.
Published: (2018-03-01) -
Generation of a GDE heterozygous mutation human embryonic stem cell line WAe001-A-14 by CRISPR/Cas9 editing
by: Guosheng Xu, et al.
Published: (2018-03-01)