Recommendations and Choices for BRCA Mutation Carriers at Risk for Ovarian Cancer: A Complicated Decision

Recommendations and Choices for BRCA Mutation Carriers at Risk for Ovarian Cancer: A Complicated Decision

Current ovarian cancer screening guidelines in high-risk women vary according to different organizations. Risk reducing surgery remains the gold standard for definitive treatment in BRCA mutation carriers, but research advancements have created more short-term options for patients to consider. The d...

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Bibliographic Details
Main Authors: Kelsey E. Lewis, Karen H. Lu, Amber M. Klimczak, Samuel C. Mok
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Cancers
Subjects:
BRCA
ovarian cancer
risk-reducing surgery
CA-125
screening guidelines
Online Access:http://www.mdpi.com/2072-6694/10/2/57
Description
Summary:Current ovarian cancer screening guidelines in high-risk women vary according to different organizations. Risk reducing surgery remains the gold standard for definitive treatment in BRCA mutation carriers, but research advancements have created more short-term options for patients to consider. The decisions involved in how a woman manages her BRCA mutation status can cause a great deal of stress and worry due to the imperfect therapy options. The goal of this review was to critically analyze the screening recommendations and alternative options for high-risk ovarian cancer patients and evaluate how these discrepancies and choices affect a woman’s management decisions.
ISSN:2072-6694

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