Encephalitis due to antibodies to voltage gated potassium channel (VGKC) with cerebellar involvement in a teenager

• Main Authors: Megan M Langille, Jay Desai
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2015-01-01
• Series: Annals of Indian Academy of Neurology
• Subjects: Antibodies to voltage gated potassium channel; anti-VGKC; encephalitis; voltage gated potassium channel; VGKC
• Online Access: http://www.annalsofian.org/article.asp?issn=0972-2327;year=2015;volume=18;issue=2;spage=238;epage=239;aulast=Langille

Encephalitis due to antibodies to voltage gated potassium channel (VGKC) typically presents with limbic encephalitis and medial temporal lobe involvement on neuroimaging. We describe a case of 13 year girl female with encephalitis due to antibodies to VGKC with signal changes in the cerebellar dentate nuclei bilaterally and clinical features that suggested predominant cerebellar involvement. These have never been reported previously in the literature. Our case expands the phenotypic spectrum of this rare condition.