Human cytomegalovirus gene UL76 induces IL-8 expression through activation of the DNA damage response.
Human cytomegalovirus (HCMV), a β-herpesvirus, has evolved many strategies to subvert both innate and adaptive host immunity in order to ensure its survival and propagation within the host. Induction of IL-8 is particularly important during HCMV infection as neutrophils, primarily attracted by IL-8,...
Main Authors: | Helena Costa, Rute Nascimento, John Sinclair, Robert Michael Evans Parkhouse |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-09-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC3771893?pdf=render |
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